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Integrated analysis of RNA-binding proteins in human colorectal cancer.
Fan X, Liu L, Shi Y, Guo F, Wang H, Zhao X, Zhong D, Li G. Fan X, et al. World J Surg Oncol. 2020 Aug 22;18(1):222. doi: 10.1186/s12957-020-01995-5. World J Surg Oncol. 2020. PMID: 32828126 Free PMC article.
BACKGROUND: Although RNA-binding proteins play an essential role in a variety of different tumours, there are still limited efforts made to systematically analyse the role of RNA-binding proteins (RBPs) in the survival of colorectal cancer (CRC) patients. METHODS: Analysis …
BACKGROUND: Although RNA-binding proteins play an essential role in a variety of different tumours, there are still limited efforts made to …
Tudor domain-containing protein 4 as a potential cancer/testis antigen in liver cancer.
Yoon H, Lee H, Kim HJ, You KT, Park YN, Kim H, Kim H. Yoon H, et al. Tohoku J Exp Med. 2011 May;224(1):41-6. doi: 10.1620/tjem.224.41. Tohoku J Exp Med. 2011. PMID: 21515969 Free article.
Cancer/testis (CT) antigens are expressed in the testis and cancerous tissues, but not in adult somatic cells. ...In conclusion, TDRD4 mRNA is expressed in a subset of liver cancers, and TDRD4 is a candidate CT antigen for liver cancer....
Cancer/testis (CT) antigens are expressed in the testis and cancerous tissues, but not in adult somatic cells. ...In conclusio …
MIWI N-terminal arginines orchestrate generation of functional pachytene piRNAs and spermiogenesis.
Vrettos N, Oppelt J, Zoch A, Sgourdou P, Yoshida H, Song B, Fink R, O'Carroll D, Mourelatos Z. Vrettos N, et al. Nucleic Acids Res. 2024 Mar 23:gkae193. doi: 10.1093/nar/gkae193. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38520410
Using mouse MIWI (PIWIL1) as paradigm, we demonstrate that the NTRs are essential for spermatogenesis through the regulation of transposons and gene expression. The loss of TDRD5 and TDRKH interaction with MIWI results in attenuation of piRNA amplification. ...
Using mouse MIWI (PIWIL1) as paradigm, we demonstrate that the NTRs are essential for spermatogenesis through the regulation of transposons …
Optical Genome Mapping Identifies Novel Recurrent Structural Alterations in Childhood ETV6::RUNX1+ and High Hyperdiploid Acute Lymphoblastic Leukemia.
Brandes D, Yasin L, Nebral K, Ebler J, Schinnerl D, Picard D, Bergmann AK, Alam J, Köhrer S, Haas OA, Attarbaschi A, Marschall T, Stanulla M, Borkhardt A, Brozou T, Fischer U, Wagener R. Brandes D, et al. Hemasphere. 2023 Jul 17;7(8):e925. doi: 10.1097/HS9.0000000000000925. eCollection 2023 Aug. Hemasphere. 2023. PMID: 37469802 Free PMC article.
The mutational landscape of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), the most common pediatric cancer, is not fully described partially because commonly applied short-read next generation sequencing has a limited ability to identify structural variations. . …
The mutational landscape of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), the most common pediatric cancer, is not fully d …
A prognostic model for oral squamous cell carcinoma using 7 genes related to tumor mutational burden.
Wu F, Du Y, Hou X, Cheng W. Wu F, et al. BMC Oral Health. 2022 Apr 29;22(1):152. doi: 10.1186/s12903-022-02193-3. BMC Oral Health. 2022. PMID: 35488327 Free PMC article.
Tumor mutational burden (TMB) is a novel prognostic biomarker for various cancers. We intended to explore the relationship between TMB-related genes and the prognosis of OSCC and to construct a prognostic model. ...RESULTS: Seven TMB-related DEGs (CTSG, COL6A5, GRIA3, CCL2 …
Tumor mutational burden (TMB) is a novel prognostic biomarker for various cancers. We intended to explore the relationship between TM …
Genome‑wide investigation of the clinical implications and molecular mechanism of long noncoding RNA LINC00668 and protein‑coding genes in hepatocellular carcinoma.
Wang X, Zhou X, Liu J, Liu Z, Zhang L, Gong Y, Huang J, Yu L, Wang Q, Yang C, Liao X, Yu T, Han C, Zhu G, Ye X, Peng T. Wang X, et al. Int J Oncol. 2019 Oct;55(4):860-878. doi: 10.3892/ijo.2019.4858. Epub 2019 Aug 14. Int J Oncol. 2019. PMID: 31432149 Free PMC article.
The top 10 PCGs identified were: Pyrimidineregic receptor P2Y4 (P2RY4), signal peptidase complex subunit 2 (SPCS2), family with sequence similarity 86 member C1 (FAM86C1), tudor domain containing 5 (TDRD5), ferritin light chain (FTL), stratifin (SFN), nucleolar complex ass …
The top 10 PCGs identified were: Pyrimidineregic receptor P2Y4 (P2RY4), signal peptidase complex subunit 2 (SPCS2), family with sequence sim …
Development and validation of an RBP gene signature for prognosis prediction in colorectal cancer based on WGCNA.
Cao L, Duan L, Zhang R, Yang W, Yang N, Huang W, Chen X, Wang N, Niu L, Zhou W, Chen J, Li Y, Zhang Y, Liu J, Fan D, Liu H. Cao L, et al. Hereditas. 2023 Mar 10;160(1):10. doi: 10.1186/s41065-023-00274-z. Hereditas. 2023. PMID: 36895014 Free PMC article.
BACKGROUND: RNA binding proteins (RBPs) have been implicated in oncogenesis and progression in various cancers. However, the potential value of RBPs as prognostic indicators and therapeutic targets in colorectal cancer (CRC) requires further investigation. ...Noscap …
BACKGROUND: RNA binding proteins (RBPs) have been implicated in oncogenesis and progression in various cancers. However, the potentia …