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Response and acquired resistance to MET inhibitors in de novo MET fusion-positive advanced non-small cell lung cancer.
Kang J, Deng QM, Feng W, Chen ZH, Su JW, Chen HJ, Wang WX, Zhang S, Wang Q, Chen Z, Zhong WZ, Xu CW, Yang JJ. Kang J, et al. Lung Cancer. 2023 Apr;178:66-74. doi: 10.1016/j.lungcan.2023.01.017. Epub 2023 Feb 1. Lung Cancer. 2023. PMID: 36806896 Free article.
OBJECTIVES: De novo mesenchymal-to-epithelial transition (MET) gene fusions in non-small cell lung cancer (NSCLC) are a promising target for MET tyrosine kinase inhibitors (TKIs). ...RESULTS: We identified 13 (0.29 %, 13/4429) patients with de novo MET fusions and found EP …
OBJECTIVES: De novo mesenchymal-to-epithelial transition (MET) gene fusions in non-small cell lung cancer (NSCLC) are a promising tar …
THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death.
Balakrishnan MP, Cilenti L, Ambivero C, Goto Y, Takata M, Turkson J, Li XS, Zervos AS. Balakrishnan MP, et al. Biochem Biophys Res Commun. 2011 Jan 7;404(1):195-200. doi: 10.1016/j.bbrc.2010.11.092. Epub 2010 Nov 24. Biochem Biophys Res Commun. 2011. PMID: 21110952 Free PMC article.
In this report, we expanded our studies on the properties and function of THAP5 in human melanoma cells. THAP5 was expressed in primary human melanocytes as well as in all melanoma cell lines that were tested. ...The induction of THAP5 correlated with a signi …
In this report, we expanded our studies on the properties and function of THAP5 in human melanoma cells. THAP5 was expressed i …