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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1997 1
1998 1
1999 4
2000 2
2001 3
2002 5
2003 1
2004 4
2005 5
2006 5
2007 4
2008 14
2009 20
2010 26
2011 28
2012 24
2013 27
2014 27
2015 37
2016 44
2017 40
2018 38
2019 34
2020 42
2021 54
2022 55
2023 45
2024 11

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526 results

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Page 1
TNFAIP3 promotes ALDH-positive breast cancer stem cells through FGFR1/MEK/ERK pathway.
Feng W, Gao M, Yang M, Li X, Gan Z, Wu T, Lin Y, He T. Feng W, et al. Med Oncol. 2022 Sep 29;39(12):230. doi: 10.1007/s12032-022-01844-3. Med Oncol. 2022. PMID: 36175778
In our prior study, we found that tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is necessary for fibroblast growth factors receptor 1 (FGFR1) signaling-promoted tumor growth and progression in breast cancer (BC). ...Moreover, ALDH-positive BCSCs were decre …
In our prior study, we found that tumor necrosis factor alpha-induced protein 3 (TNFAIP3) is necessary for fibroblast growth factors …
TNFAIP3 mediates FGFR1 activation-induced breast cancer angiogenesis by promoting VEGFA expression and secretion.
Gao M, Li X, Yang M, Feng W, Lin Y, He T. Gao M, et al. Clin Transl Oncol. 2022 Dec;24(12):2453-2465. doi: 10.1007/s12094-022-02918-4. Epub 2022 Aug 24. Clin Transl Oncol. 2022. PMID: 36002765
RNA-seq analysis of TNFAIP3 downstreams differential genes after TNFAIP3 knockdown. The expression and secretion of VEGFA after FGFR1 activation in breast cancer cells were detected by qPCR, Western blot, and ELISA. ...CONCLUSION: TNFAIP3 promotes brea …
RNA-seq analysis of TNFAIP3 downstreams differential genes after TNFAIP3 knockdown. The expression and secretion of VEGFA afte …
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL. Han MT, et al. Am J Cancer Res. 2023 Apr 15;13(4):1533-1546. eCollection 2023. Am J Cancer Res. 2023. PMID: 37168345 Free PMC article.
In addition, we demonstrated the effects of TNFAIP3 on prostate cancer cell apoptosis, migration and proliferation to elucidate the mechanism of ZY-444. ...Overall, these findings highlighted TNFAIP3 as a tumor suppressor gene in the regulation of the progres …
In addition, we demonstrated the effects of TNFAIP3 on prostate cancer cell apoptosis, migration and proliferation to elucidat …
Multifaceted roles of TAX1BP1 in autophagy.
White J, Suklabaidya S, Vo MT, Choi YB, Harhaj EW. White J, et al. Autophagy. 2023 Jan;19(1):44-53. doi: 10.1080/15548627.2022.2070331. Epub 2022 May 9. Autophagy. 2023. PMID: 35470757 Free PMC article. Review.
In this review, we will discuss and integrate recent findings related to the autophagy function of TAX1BP1 and highlight outstanding questions regarding its functions in autophagy and regulation of innate immunity and host defense.Abbreviations: ATG: autophagy related; CALCOCO: c …
In this review, we will discuss and integrate recent findings related to the autophagy function of TAX1BP1 and highlight outstanding questio …
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block "eat-me" signal.
Luo M, Wang X, Wu S, Yang C, Su Q, Huang L, Fu K, An S, Xie F, To KKW, Wang F, Fu L. Luo M, et al. Signal Transduct Target Ther. 2023 Aug 23;8(1):312. doi: 10.1038/s41392-023-01545-x. Signal Transduct Target Ther. 2023. PMID: 37607946 Free PMC article.
Immune checkpoint inhibitors (ICIs) have induced durable clinical responses in a subset of patients with colorectal cancer (CRC). However, the dis-satisfactory response rate and the lack of appropriate biomarkers for selecting suitable patients to be treated with ICIs pose …
Immune checkpoint inhibitors (ICIs) have induced durable clinical responses in a subset of patients with colorectal cancer (CRC). How …
The Ubiquitin System and A20: Implications in Health and Disease.
Mooney EC, Sahingur SE. Mooney EC, et al. J Dent Res. 2021 Jan;100(1):10-20. doi: 10.1177/0022034520949486. Epub 2020 Aug 27. J Dent Res. 2021. PMID: 32853526 Free PMC article. Review.
Through the cooperative actions of E3 ubiquitin ligases and deubiquitinases, ubiquitin modifications are implicated in several biological processes, including proteasomal degradation, transcriptional regulation, regulation of protein-protein interactions, endocytosis, autophagy, …
Through the cooperative actions of E3 ubiquitin ligases and deubiquitinases, ubiquitin modifications are implicated in several biological pr …
Clinical and Basic Evaluation of the Effects of Upregulated TNFAIP3 Expression on Colorectal Cancer.
Li J, Ren S, Zhang Y, Wu B, He M, Shan Z, Liu Y, Wang Y. Li J, et al. Dis Markers. 2022 Aug 18;2022:1263530. doi: 10.1155/2022/1263530. eCollection 2022. Dis Markers. 2022. PMID: 36033828 Free PMC article.
OBJECTIVE: To assess the TNFAIP3 and nuclear factor kappaB (NFkappaB) protein expressions in colorectal cancer (CRC) tissue and to analyze the association of these proteins with the clinical pathological characteristics of CRC. ...For basic experiment, we establishe …
OBJECTIVE: To assess the TNFAIP3 and nuclear factor kappaB (NFkappaB) protein expressions in colorectal cancer (CRC) tissue an …
Immunohistochemical Assessment of TNFAIP3/A20 Expression Correlates With Early Tumorigenesis in Breast Cancer.
Sharif-Askari FS, Al-Khayyal N, Talaat I, Sharif-Askari NS, Rawat S, Jundi M, SyrjÄnen K, Hamoudi R, Bendardaf R. Sharif-Askari FS, et al. Anticancer Res. 2021 Feb;41(2):739-745. doi: 10.21873/anticanres.14825. Anticancer Res. 2021. PMID: 33517278
BACKGROUND/AIM: Limited data exist on the expression pattern of TNFAIP3/A20, as assayed by immunohistochemistry (IHC), in breast cancer tissues. This study aimed to assess A20 expression pattern in breast cancer. MATERIALS AND METHODS: The expression of A20 w …
BACKGROUND/AIM: Limited data exist on the expression pattern of TNFAIP3/A20, as assayed by immunohistochemistry (IHC), in breast c …
The dual roles of A20 in cancer.
Shi Y, Wang X, Wang J, Wang X, Zhou H, Zhang L. Shi Y, et al. Cancer Lett. 2021 Jul 28;511:26-35. doi: 10.1016/j.canlet.2021.04.017. Epub 2021 Apr 29. Cancer Lett. 2021. PMID: 33933552 Review.
Subsequent studies revealed the dual roles of A20 in solid cancers. This review focuses on the roles of A20 in different cancer types to demonstrate that the effects of A20 are cancer type-dependent. ...Exploration of the actions and molecular mechanisms of A …
Subsequent studies revealed the dual roles of A20 in solid cancers. This review focuses on the roles of A20 in different cancer …
526 results