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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 3
1998 12
1999 44
2000 39
2001 63
2002 51
2003 57
2004 71
2005 66
2006 54
2007 54
2008 68
2009 61
2010 70
2011 84
2012 81
2013 62
2014 61
2015 49
2016 29
2017 44
2018 53
2019 54
2020 42
2021 41
2022 42
2023 25
2024 16

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1,263 results

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Page 1
Comprehensive genomic profiles of small cell lung cancer.
George J, Lim JS, Jang SJ, Cun Y, Ozretić L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco G, Müller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, Vaka D, Torres A, Wang MS, Korbel JO, Menon R, Chun SM, Kim D, Wilkerson M, Hayes N, Engelmann D, Pützer B, Bos M, Michels S, Vlasic I, Seidel D, Pinther B, Schaub P, Becker C, Altmüller J, Yokota J, Kohno T, Iwakawa R, Tsuta K, Noguchi M, Muley T, Hoffmann H, Schnabel PA, Petersen I, Chen Y, Soltermann A, Tischler V, Choi CM, Kim YH, Massion PP, Zou Y, Jovanovic D, Kontic M, Wright GM, Russell PA, Solomon B, Koch I, Lindner M, Muscarella LA, la Torre A, Field JK, Jakopovic M, Knezevic J, Castaños-Vélez E, Roz L, Pastorino U, Brustugun OT, Lund-Iversen M, Thunnissen E, Köhler J, Schuler M, Botling J, Sandelin M, Sanchez-Cespedes M, Salvesen HB, Achter V, Lang U, Bogus M, Schneider PM, Zander T, Ansén S, Hallek M, Wolf J, Vingron M, Yatabe Y, Travis WD, Nürnberg P, Reinhardt C, Perner S, Heukamp L, Büttner R, Haas SA, Brambilla E, Peifer M, Sage J, Thomas RK. George J, et al. Nature. 2015 Aug 6;524(7563):47-53. doi: 10.1038/nature14664. Epub 2015 Jul 13. Nature. 2015. PMID: 26168399 Free PMC article.
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tumours analysed we found bi-allelic inactivation of TP53 and RB1, sometimes by complex genomic rearrangements. ...Thus, loss of the tumour sup …
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. In nearly all the tum …
Clinical implications of the deregulated TP73 isoforms expression in cancer.
Rodríguez N, Peláez A, Barderas R, Domínguez G. Rodríguez N, et al. Clin Transl Oncol. 2018 Jul;20(7):827-836. doi: 10.1007/s12094-017-1802-3. Epub 2017 Dec 11. Clin Transl Oncol. 2018. PMID: 29230693 Review.
TP73 is a member of the TP53 family whose expression has been observed altered in most human cancers and associated with the prognosis. ...In this revision, we focus on the evidence that may support TP73 variants as prognostic markers in cancer. Nowada …
TP73 is a member of the TP53 family whose expression has been observed altered in most human cancers and associated with the p …
Role of long non-coding RNA TP73-AS1 in cancer.
Chen C, Shu L, Zou W. Chen C, et al. Biosci Rep. 2019 Oct 30;39(10):BSR20192274. doi: 10.1042/BSR20192274. Biosci Rep. 2019. PMID: 31652459 Free PMC article.
This review summarizes current findings on the role of TP73-AS1 and its signaling pathways in various cancers, including glioma, esophageal squamous cell carcinoma (ESCC), hepatocellular carcinoma (HCC), colorectal cancer (CRC), osteosarcoma, gastric cance …
This review summarizes current findings on the role of TP73-AS1 and its signaling pathways in various cancers, including gliom …
Silencing of TP73-AS1 impairs prostate cancer cell proliferation and induces apoptosis via regulation of TP73.
Arslan A, Batar B, Temiz E, Tozkir H, Koyuncu I, Bozgeyik E. Arslan A, et al. Mol Biol Rep. 2022 Jul;49(7):6859-6869. doi: 10.1007/s11033-022-07141-6. Epub 2022 Feb 9. Mol Biol Rep. 2022. PMID: 35138524
However, whether TP73-AS1 contributes to prostate cancer progression has not been reported yet. ...CONCLUSIONS: Our findings provide novel evidence that suggests a chief regulatory role for the TP73-TP73-AS1 axis in prostate cancer development a …
However, whether TP73-AS1 contributes to prostate cancer progression has not been reported yet. ...CONCLUSIONS: Our findings p …
LncRNA TP73-AS1 is a novel regulator in cervical cancer via miR-329-3p/ARF1 axis.
Xu J, Zhang J. Xu J, et al. J Cell Biochem. 2020 Jan;121(1):344-352. doi: 10.1002/jcb.29181. Epub 2019 Jun 24. J Cell Biochem. 2020. PMID: 31232491
However, the function and mechanism of many lncRNAs still call for further research. Tumor Protein P73 Antisense RNA 1 (TP73-AS1) is no exception. LncRNA TP73-AS1 has been found to promote cancer progressions in various cancers. ...TP73-AS1 migh …
However, the function and mechanism of many lncRNAs still call for further research. Tumor Protein P73 Antisense RNA 1 (TP73-AS1) is …
The TP73 complex network: ready for clinical translation in cancer?
Soldevilla B, Millán CS, Bonilla F, Domínguez G. Soldevilla B, et al. Genes Chromosomes Cancer. 2013 Nov;52(11):989-1006. doi: 10.1002/gcc.22095. Epub 2013 Aug 1. Genes Chromosomes Cancer. 2013. PMID: 23913810 Review.
TP73 is a member of the TP53 family, whose deregulated expression has been reported in a wide variety of cancers and linked to patients' outcome. ...In addition, we comment on current pharmacological approaches targeting the TP73 pathway and those affecting t …
TP73 is a member of the TP53 family, whose deregulated expression has been reported in a wide variety of cancers and linked to …
TP73 G4C14-A4T14 polymorphism and cancer susceptibility: evidence from 36 case-control studies.
Meng J, Wang S, Zhang M, Fan S, Zhang L, Liang C. Meng J, et al. Biosci Rep. 2018 Dec 14;38(6):BSR20181452. doi: 10.1042/BSR20181452. Print 2018 Dec 21. Biosci Rep. 2018. PMID: 30420492 Free PMC article.
In silico analysis revealed that the expression of TP73 in cervical cancer tissue is higher than it in corresponding normal tissue, as well as in cervical cancer. All in all, TP73 G4C14-A4T14 polymorphism causes an upgrade cancer risk, especiall …
In silico analysis revealed that the expression of TP73 in cervical cancer tissue is higher than it in corresponding normal ti …
miR-320a promotes p53-dependent apoptosis of prostate cancer cells by negatively regulating TP73-AS1 invitro.
Bozgeyik E, Arslan A, Temiz E, Batar B, Koyuncu I, Tozkir H. Bozgeyik E, et al. Biochem Biophys Res Commun. 2022 Sep 3;619:130-136. doi: 10.1016/j.bbrc.2022.06.034. Epub 2022 Jun 13. Biochem Biophys Res Commun. 2022. PMID: 35760009
TP73 antisense RNA 1 (TP73-AS1) is an oncogenic long non-coding RNA that is activated in several types of cancers. It has been shown that the activity of TP73-AS1 is controlled by several miRNAs, but post-transcriptional mechanisms that regulate TP7 …
TP73 antisense RNA 1 (TP73-AS1) is an oncogenic long non-coding RNA that is activated in several types of cancers. It h …
TP73-AS1 promotes breast cancer cell proliferation through miR-200a-mediated TFAM inhibition.
Yao J, Xu F, Zhang D, Yi W, Chen X, Chen G, Zhou E. Yao J, et al. J Cell Biochem. 2018 Jan;119(1):680-690. doi: 10.1002/jcb.26231. Epub 2017 Oct 5. J Cell Biochem. 2018. PMID: 28639399
An abnormal change of TP73-AS1 expression was noticed in cancers. The effects of TP73-AS1 in breast cancer (BC) growth and the underlying mechanism remain unclear so far. ...TP73-AS1 knocking down suppressed human BC cell proliferation in vitro …
An abnormal change of TP73-AS1 expression was noticed in cancers. The effects of TP73-AS1 in breast cancer (BC) …
Meta-analysis of TP73 polymorphism and cervical cancer.
Feng H, Sui L, Du M, Wang Q. Feng H, et al. Genet Mol Res. 2017 Jan 23;16(1). doi: 10.4238/gmr16016571. Genet Mol Res. 2017. PMID: 28128397 Free article.
The aim of this study was to investigate the tumor protein p73 (TP73) G4C14-A4T14 polymorphism and to perform a meta-analysis to assess TP73 expression in cervical cancer and precancerous tissue. ...This elevated expression may play an important role in the o …
The aim of this study was to investigate the tumor protein p73 (TP73) G4C14-A4T14 polymorphism and to perform a meta-analysis to asse …
1,263 results