Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2000 1
2001 3
2002 3
2003 5
2004 4
2005 4
2006 6
2007 8
2008 2
2009 5
2010 9
2011 11
2012 9
2013 10
2014 10
2015 3
2016 7
2017 8
2018 15
2019 11
2020 20
2021 14
2022 9
2023 14
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

175 results

Results by year

Filters applied: . Clear all
Page 1
TRPV6 as A Target for Cancer Therapy.
Stewart JM. Stewart JM. J Cancer. 2020 Jan 1;11(2):374-387. doi: 10.7150/jca.31640. eCollection 2020. J Cancer. 2020. PMID: 31897233 Free PMC article. Review.
TRPV6 can be greatly elevated in a number of cancers deriving from epithelia and considerable study has been made of its role in the cancer phenotype where calcium control is dysfunctional. This review compiles and updates recent published work on TRPV6 …
TRPV6 can be greatly elevated in a number of cancers deriving from epithelia and considerable study has been made of its role …
The TRPV6 Calcium Channel and Its Relationship with Cancer.
Wang Y, Deng X, Zhang R, Lyu H, Xiao S, Guo D, Ali DW, Michalak M, Zhou C, Chen XZ, Tang J. Wang Y, et al. Biology (Basel). 2024 Mar 5;13(3):168. doi: 10.3390/biology13030168. Biology (Basel). 2024. PMID: 38534438 Free PMC article. Review.
Transient receptor potential vanilloid-6 (TRPV6) is a cation channel belonging to the TRP superfamily, specifically the vanilloid subfamily, and is the sixth member of this subfamily. ...Several pieces of evidence suggest that it is upregulated in the advanced stages of th …
Transient receptor potential vanilloid-6 (TRPV6) is a cation channel belonging to the TRP superfamily, specifically the vanilloid sub …
Calcium channel TRPV6 promotes breast cancer metastasis by NFATC2IP.
Xu X, Li N, Wang Y, Yu J, Mi J. Xu X, et al. Cancer Lett. 2021 Oct 28;519:150-160. doi: 10.1016/j.canlet.2021.07.017. Epub 2021 Jul 13. Cancer Lett. 2021. PMID: 34265397
Calcium channel TRPV6 upregulation is associated with poor prognosis of breast cancer by promoting invasion and metastasis, and TRPV6 is a potential target for breast cancer therapy. However, the mechanism by which TRPV6 promotes breast metastas …
Calcium channel TRPV6 upregulation is associated with poor prognosis of breast cancer by promoting invasion and metastasis, an …
The role of the TRPV6 channel in cancer.
Lehen'kyi V, Raphaël M, Prevarskaya N. Lehen'kyi V, et al. J Physiol. 2012 Mar 15;590(6):1369-76. doi: 10.1113/jphysiol.2011.225862. Epub 2012 Feb 13. J Physiol. 2012. PMID: 22331416 Free PMC article. Review.
Little is known about its role in initiation or progression for most of cancers, though in prostate cancer its oncogenic potential in vitro has been suggested. The most probable mechanisms involve calcium signalling in the control of processes such as proliferation …
Little is known about its role in initiation or progression for most of cancers, though in prostate cancer its oncogenic poten …
RETRACTED: TRPV6 calcium channel regulation, downstream pathways, and therapeutic targeting in cancer.
Haustrate A, Hantute-Ghesquier A, Prevarskaya N, Lehen'kyi V. Haustrate A, et al. Cell Calcium. 2019 Jun;80:117-124. doi: 10.1016/j.ceca.2019.04.006. Epub 2019 Apr 22. Cell Calcium. 2019. PMID: 31055179 Retracted. Review.
This article was retracted because of inappropriate use of confidential material and text available to one of the authors through the review of "TRPV6 As A Target For Cancer Therapy", John M Stewart, J. Cancer, online date 2019-5-13; doi:10.7150/jca.31640....
This article was retracted because of inappropriate use of confidential material and text available to one of the authors through the review …
TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression.
Wissenbach U, Niemeyer B, Himmerkus N, Fixemer T, Bonkhoff H, Flockerzi V. Wissenbach U, et al. Biochem Biophys Res Commun. 2004 Oct 1;322(4):1359-63. doi: 10.1016/j.bbrc.2004.08.042. Biochem Biophys Res Commun. 2004. PMID: 15336984 Review.
Life expectancy for patients suffering from prostate cancer is inversely correlated with the degree of extraprostatic metastasis. In order to find pharmacological tools to treat this aggressive growth it is important to define targets whose expression not only correlates w …
Life expectancy for patients suffering from prostate cancer is inversely correlated with the degree of extraprostatic metastasis. In …
TRPV6 channels.
Fecher-Trost C, Weissgerber P, Wissenbach U. Fecher-Trost C, et al. Handb Exp Pharmacol. 2014;222:359-84. doi: 10.1007/978-3-642-54215-2_14. Handb Exp Pharmacol. 2014. PMID: 24756713 Review.
Not only a very rare event in eukaryotic biology, the full-length TRPV6 protein existing in vivo comprises an amino terminus extended by 40 amino acid residues compared to the annotated truncated TRPV6 protein which has been used in most studies on TRPV6 chan …
Not only a very rare event in eukaryotic biology, the full-length TRPV6 protein existing in vivo comprises an amino terminus extended …
A Novel Anti-TRPV6 Antibody and Its Application in Cancer Diagnosis In Vitro.
Haustrate A, Mihalache A, Cordier C, Gosset P, Prevarskaya N, Lehen'kyi V. Haustrate A, et al. Int J Mol Sci. 2022 Dec 27;24(1):419. doi: 10.3390/ijms24010419. Int J Mol Sci. 2022. PMID: 36613866 Free PMC article.
One of the most important applications is immunohistochemistry using the paraffin-embedded sections from cancer resection specimens. Using prostate cancer resection specimens, we have confirmed the absence of the TRPV6 protein in both healthy and benign hyper …
One of the most important applications is immunohistochemistry using the paraffin-embedded sections from cancer resection specimens. …
Comments on the evolution of TRPV6.
Wolske K, Wyatt A, Wissenbach U. Wolske K, et al. Ann Anat. 2021 Nov;238:151753. doi: 10.1016/j.aanat.2021.151753. Epub 2021 May 6. Ann Anat. 2021. PMID: 33964462 Review.
Sequences with recognizable similarity to TRPV6 can already be found in archaebacteria. These ancient sequences show clear similarity to the ion-conducting pore of TRPV6. ...The latter effect is not observed in mice, implying that the effects due to perturbations in …
Sequences with recognizable similarity to TRPV6 can already be found in archaebacteria. These ancient sequences show clear similarity …
Calcium selective channel TRPV6: Structure, function, and implications in health and disease.
Khattar V, Wang L, Peng JB. Khattar V, et al. Gene. 2022 Apr 5;817:146192. doi: 10.1016/j.gene.2022.146192. Epub 2022 Jan 11. Gene. 2022. PMID: 35031425 Free PMC article. Review.
In addition, TRPV6 is also regulated by the level of dietary Ca(2+) and under physiological conditions such as pregnancy and lactation. ...TRPV6 is overexpressed in a wide range of human malignancies and its upregulation is strongly correlated to tumor aggressivenes …
In addition, TRPV6 is also regulated by the level of dietary Ca(2+) and under physiological conditions such as pregnancy and lactatio …
175 results