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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 1
1999 1
2001 1
2002 3
2003 2
2004 11
2005 11
2006 15
2007 34
2008 32
2009 52
2010 65
2011 94
2012 126
2013 128
2014 147
2015 175
2016 171
2017 190
2018 188
2019 200
2020 182
2021 190
2022 120
2023 113
2024 51

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2,018 results

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lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/beta-catenin signaling.
Pan J, Fang S, Tian H, Zhou C, Zhao X, Tian H, He J, Shen W, Meng X, Jin X, Gong Z. Pan J, et al. Mol Cancer. 2020 Jan 15;19(1):9. doi: 10.1186/s12943-020-1133-9. Mol Cancer. 2020. PMID: 31941509 Free PMC article.
Additionally, JPX upregulated Twist1 by competitively sponging miR-33a-5p and subsequently induced EMT and lung cancer cell invasion. Interestingly, JPX and Twist1 were coordinately upregulated in lung cancer tissues and cells. ...
Additionally, JPX upregulated Twist1 by competitively sponging miR-33a-5p and subsequently induced EMT and lung cancer cell in …
USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination.
Zhao B, Huo W, Yu X, Shi X, Lv L, Yang Y, Kang J, Li S, Wu H. Zhao B, et al. Cell Oncol (Dordr). 2023 Jun;46(3):717-733. doi: 10.1007/s13402-023-00779-9. Epub 2023 Feb 3. Cell Oncol (Dordr). 2023. PMID: 36732432 Free PMC article.
We found that the effect of USP13 in promoting the migration and invasion capacities of breast cancer cells can at least partly be achieved through its regulation of Twist1, while Twist1 can inhibit the transcriptional activity of USP13. ...Our findings show …
We found that the effect of USP13 in promoting the migration and invasion capacities of breast cancer cells can at least partly be ac …
Molecular mechanisms of TWIST1-regulated transcription in EMT and cancer metastasis.
Yu X, He T, Tong Z, Liao L, Huang S, Fakhouri WD, Edwards DP, Xu J. Yu X, et al. EMBO Rep. 2023 Nov 6;24(11):e56902. doi: 10.15252/embr.202356902. Epub 2023 Sep 8. EMBO Rep. 2023. PMID: 37680145 Free article.
TWIST1 induces epithelial-to-mesenchymal transition (EMT) to drive cancer metastasis. It is yet unclear what determines TWIST1 functions to activate or repress transcription. We found that the TWIST1 N-terminus antagonizes TWIST1-regulated gene …
TWIST1 induces epithelial-to-mesenchymal transition (EMT) to drive cancer metastasis. It is yet unclear what determines TWI …
Twist1 induces chromosomal instability (CIN) in colorectal cancer cells.
Khot M, Sreekumar D, Jahagirdar S, Kulkarni A, Hari K, Faseela EE, Sabarinathan R, Jolly MK, Sengupta K. Khot M, et al. Hum Mol Genet. 2020 Jun 27;29(10):1673-1688. doi: 10.1093/hmg/ddaa076. Hum Mol Genet. 2020. PMID: 32337580 Free PMC article.
Mathematical simulations using the RACIPE tool show a negative correlation of Twist1 with E-cadherin and BubR1. Data analyses of gene expression profiles of patient samples from The Cancer Genome Atlas (TCGA) reveal a positive correlation between Twist1 and m …
Mathematical simulations using the RACIPE tool show a negative correlation of Twist1 with E-cadherin and BubR1. Data analyses of gene …
Epithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connection.
Wu KJ, Yang MH. Wu KJ, et al. Biosci Rep. 2011 Dec;31(6):449-55. doi: 10.1042/BSR20100114. Biosci Rep. 2011. PMID: 21919891 Review.
Bmi1 is frequently overexpressed in different types of human cancers. Recent demonstration of an EMT regulator, Twist1, directly regulating the expression of Bmi1 provides a mechanistic explanation of the relationship between EMT and cancer stemness. ...This …
Bmi1 is frequently overexpressed in different types of human cancers. Recent demonstration of an EMT regulator, Twist1, direct …
Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions.
Guan T, Li M, Song Y, Chen J, Tang J, Zhang C, Wen Y, Yang X, Huang L, Zhu Y, Wang H, Ding K, Zheng J, Zhang H, Liu T. Guan T, et al. Adv Sci (Weinh). 2023 Apr;10(11):e2205873. doi: 10.1002/advs.202205873. Epub 2023 Feb 13. Adv Sci (Weinh). 2023. PMID: 36782089 Free PMC article.
TWIST1, a key transcriptional factor of epithelial-mesenchymal transition (EMT), contributes to self-renewal of cancer stem-like cells (CSCs), chemo-resistance, metastasis, and TNBC-related death. However, the mechanism by which TWIST1 is deregulated in TNBC …
TWIST1, a key transcriptional factor of epithelial-mesenchymal transition (EMT), contributes to self-renewal of cancer stem-li …
TWIST1 activates cancer stem cell marker genes to promote epithelial-mesenchymal transition and tumorigenesis in esophageal squamous cell carcinoma.
Khales SA, Mozaffari-Jovin S, Geerts D, Abbaszadegan MR. Khales SA, et al. BMC Cancer. 2022 Dec 6;22(1):1272. doi: 10.1186/s12885-022-10252-9. BMC Cancer. 2022. PMID: 36474162 Free PMC article.
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers worldwide. Overexpression of EMT master transcription factors can promote differentiated cells to undergo cancer reprogramming processes and acquire a stem cell-like status. ...RES …
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers worldwide. Overexpression of EMT master transcr …
CDC20 promotes radioresistance of prostate cancer by activating Twist1 expression.
Yang C, Ge Y, Zang Y, Xu M, Jin L, Wang Y, Xu X, Xue B, Wang Z, Wang L. Yang C, et al. Apoptosis. 2023 Dec;28(11-12):1584-1595. doi: 10.1007/s10495-023-01877-7. Epub 2023 Aug 3. Apoptosis. 2023. PMID: 37535214
Currently, radiotherapy is one of the most attractive treatments for prostate cancer (PCa) patients. However, radioresistance remains a challenging issue and the underlying mechanism is unknown. ...We demonstrated that the expression of CDC20 was increased in PCa cells by …
Currently, radiotherapy is one of the most attractive treatments for prostate cancer (PCa) patients. However, radioresistance remains …
Shake It Up Baby Now: The Changing Focus on TWIST1 and Epithelial to Mesenchymal Transition in Cancer and Other Diseases.
Mirjat D, Kashif M, Roberts CM. Mirjat D, et al. Int J Mol Sci. 2023 Dec 16;24(24):17539. doi: 10.3390/ijms242417539. Int J Mol Sci. 2023. PMID: 38139368 Free PMC article. Review.
In recent years, the roles of TWIST1 and other EMT factors in cancer have expanded greatly as our understanding of tumor progression has advanced. ...In this review, we highlight non-metastatic roles for TWIST1 and related EMT factors in cancer and oth …
In recent years, the roles of TWIST1 and other EMT factors in cancer have expanded greatly as our understanding of tumor progr …
Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression.
Xu Y, Qin L, Sun T, Wu H, He T, Yang Z, Mo Q, Liao L, Xu J. Xu Y, et al. Oncogene. 2017 Feb 23;36(8):1157-1166. doi: 10.1038/onc.2016.286. Epub 2016 Aug 15. Oncogene. 2017. PMID: 27524420 Free PMC article.
Foxa1 expression is linked with luminal breast cancer (LBC) with good prognosis, whereas Twist1 expression is associated with basal-like breast cancer (BLBC) with poor prognosis owing to its role in promoting epithelial-to-mesenchymal transition (EMT), invasi …
Foxa1 expression is linked with luminal breast cancer (LBC) with good prognosis, whereas Twist1 expression is associated with …
2,018 results