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A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
King KM, Damaraju VL, Vickers MF, Yao SY, Lang T, Tackaberry TE, Mowles DA, Ng AM, Young JD, Cass CE. King KM, et al. Among authors: tackaberry te. Mol Pharmacol. 2006 Jan;69(1):346-53. doi: 10.1124/mol.105.015768. Epub 2005 Oct 18. Mol Pharmacol. 2006. PMID: 16234483
Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.
Damaraju S, Zhang J, Visser F, Tackaberry T, Dufour J, Smith KM, Slugoski M, Ritzel MW, Baldwin SA, Young JD, Cass CE. Damaraju S, et al. Among authors: tackaberry t. Pharmacogenet Genomics. 2005 Mar;15(3):173-82. doi: 10.1097/01213011-200503000-00006. Pharmacogenet Genomics. 2005. PMID: 15861042
Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.
Visser F, Sun L, Damaraju V, Tackaberry T, Peng Y, Robins MJ, Baldwin SA, Young JD, Cass CE. Visser F, et al. Among authors: tackaberry t. J Biol Chem. 2007 May 11;282(19):14148-57. doi: 10.1074/jbc.M701735200. Epub 2007 Mar 22. J Biol Chem. 2007. PMID: 17379602 Free article.
Improved syntheses of 5'-S-(2-aminoethyl)-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), analogues, and fluorescent probe conjugates: analysis of cell-surface human equilibrative nucleoside transporter 1 (hENT1) levels for prediction of the antitumor efficacy of gemcitabine.
Robins MJ, Peng Y, Damaraju VL, Mowles D, Barron G, Tackaberry T, Young JD, Cass CE. Robins MJ, et al. Among authors: tackaberry t. J Med Chem. 2010 Aug 26;53(16):6040-53. doi: 10.1021/jm100432w. J Med Chem. 2010. PMID: 20718495