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73 results

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TAF10 and TAF10b partially redundant roles during Drosophila melanogaster morphogenesis.
Pahi Z, Borsos BN, Vedelek B, Shidlovskii YV, Georgieva SG, Boros IM, Pankotai T. Pahi Z, et al. Transcription. 2017;8(5):297-306. doi: 10.1080/21541264.2017.1327836. Epub 2017 Aug 25. Transcription. 2017. PMID: 28841365 Free PMC article.
Here, we report the functional similarities and differences of TAF10 and TAF10b, the two TAF10 orthologs of Drosophila melanogaster. ...
Here, we report the functional similarities and differences of TAF10 and TAF10b, the two TAF10 orthologs of Drosophila melanog …
TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.
Papadopoulos P, Gutiérrez L, Demmers J, Scheer E, Pourfarzad F, Papageorgiou DN, Karkoulia E, Strouboulis J, van de Werken HJ, van der Linden R, Vandenberghe P, Dekkers DH, Philipsen S, Grosveld F, Tora L. Papadopoulos P, et al. Mol Cell Biol. 2015 Jun;35(12):2103-18. doi: 10.1128/MCB.01370-14. Epub 2015 Apr 13. Mol Cell Biol. 2015. PMID: 25870109 Free PMC article.
By ablating TAF10 specifically in erythroid cells in vivo, we observed a differentiation block accompanied by deregulated GATA1 target genes, including Gata1 itself, suggesting functional cross talk between GATA1 and TAF10. Additionally, we analyzed by mass spectrom …
By ablating TAF10 specifically in erythroid cells in vivo, we observed a differentiation block accompanied by deregulated GATA1 targe …
TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis.
Indra AK, Mohan WS 2nd, Frontini M, Scheer E, Messaddeq N, Metzger D, Tora L. Indra AK, et al. Dev Biol. 2005 Sep 1;285(1):28-37. doi: 10.1016/j.ydbio.2005.05.043. Dev Biol. 2005. PMID: 16039642 Free article.
SAGA, TFTC, STAGA and PCAF/GCN5). TAF10 is an essential transcription factor during very early stages of mouse embryo development. To study the in vivo function of TAF10 in cellular differentiation and proliferation at later stages, the role of TAF10 was anal …
SAGA, TFTC, STAGA and PCAF/GCN5). TAF10 is an essential transcription factor during very early stages of mouse embryo development. To …
Small molecule Z363 co-regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth.
Xiong Y, Wang L, Xu S, Fu B, Che Y, Zaky MY, Tian R, Yao R, Guo D, Sha Z, Lin F, Lin X, Wu H. Xiong Y, et al. Clin Transl Med. 2023 Jan;13(1):e1153. doi: 10.1002/ctm2.1153. Clin Transl Med. 2023. PMID: 36639831 Free PMC article.
Western blot was used to analyzed the expressions of MYC and TATA-binding proteinassociated factors 10 (TAF10) in cancer cells (MCF7, A549, HepG2 cells) Cell culture studies were performed to determine the mechanisms by which small molecules (Z363119456, Z363) affects MYC …
Western blot was used to analyzed the expressions of MYC and TATA-binding proteinassociated factors 10 (TAF10) in cancer cells (MCF7, …
TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice.
Mohan WS Jr, Scheer E, Wendling O, Metzger D, Tora L. Mohan WS Jr, et al. Mol Cell Biol. 2003 Jun;23(12):4307-18. doi: 10.1128/MCB.23.12.4307-4318.2003. Mol Cell Biol. 2003. PMID: 12773572 Free PMC article.
Interestingly, no TAF10(-/-) animals were born from intercrosses of TAF10(+/-) mice, indicating that TAF10 is required for embryogenesis. ...TAF10-deficient cells express normal levels of TBP and TAFs other than TAF10 but contain only partially …
Interestingly, no TAF10(-/-) animals were born from intercrosses of TAF10(+/-) mice, indicating that TAF10 is required …
The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
Bardot P, Vincent SD, Fournier M, Hubaud A, Joint M, Tora L, Pourquié O. Bardot P, et al. Development. 2017 Oct 15;144(20):3808-3818. doi: 10.1242/dev.146902. Epub 2017 Sep 11. Development. 2017. PMID: 28893950 Free PMC article.
In vitro data suggest that TFIID is the general transcription factor that nucleates PIC formation at promoters. Here we show that TAF10, a subunit of TFIID and of the transcriptional co-activator SAGA, is required for the assembly of these complexes in the mouse embryo. We …
In vitro data suggest that TFIID is the general transcription factor that nucleates PIC formation at promoters. Here we show that TAF10 …
LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation.
Iturbide A, Pascual-Reguant L, Fargas L, Cebrià JP, Alsina B, García de Herreros A, Peiró S. Iturbide A, et al. Mol Cell. 2015 Jun 4;58(5):755-66. doi: 10.1016/j.molcel.2015.04.012. Epub 2015 May 7. Mol Cell. 2015. PMID: 25959397 Free article.
Using an unbiased proteomic approach, we have identified methylated TAF10, a member of the TFIID complex, as a LOXL2 substrate. LOXL2 oxidation of TAF10 induces its release from its promoters, leading to a block in TFIID-dependent gene transcription. ...During zebra …
Using an unbiased proteomic approach, we have identified methylated TAF10, a member of the TFIID complex, as a LOXL2 substrate. LOXL2 …
Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Trowitzsch S, Viola C, Scheer E, Conic S, Chavant V, Fournier M, Papai G, Ebong IO, Schaffitzel C, Zou J, Haffke M, Rappsilber J, Robinson CV, Schultz P, Tora L, Berger I. Trowitzsch S, et al. Nat Commun. 2015 Jan 14;6:6011. doi: 10.1038/ncomms7011. Nat Commun. 2015. PMID: 25586196 Free PMC article.
Here we describe a heterotrimeric TFIID subcomplex consisting of the TAF2, TAF8 and TAF10 proteins, which assembles in the cytoplasm. Using native mass spectrometry, we define the interactions between the TAFs and uncover a central role for TAF8 in nucleating the complex. …
Here we describe a heterotrimeric TFIID subcomplex consisting of the TAF2, TAF8 and TAF10 proteins, which assembles in the cytoplasm. …
Gene-specific modulation of TAF10 function by SET9-mediated methylation.
Kouskouti A, Scheer E, Staub A, Tora L, Talianidis I. Kouskouti A, et al. Mol Cell. 2004 Apr 23;14(2):175-82. doi: 10.1016/s1097-2765(04)00182-0. Mol Cell. 2004. PMID: 15099517 Free article.
Methylated TAF10 has an increased affinity for RNA polymerase II, pointing to a direct role of this modification in preinitiation complex formation. Reporter assays and studies on TAF10 null F9 cells expressing a methylation-deficient TAF10 mutant revealed th …
Methylated TAF10 has an increased affinity for RNA polymerase II, pointing to a direct role of this modification in preinitiation com …
Cloning and bioinformatic analysis of full-length novel pepper (Capsicum annuum) genes TAF10 and TAF13.
Wen JF, Huo JL, Chen HX, Ma CH, Jiang H, Zhu HS, Zhou H, Deng MH. Wen JF, et al. Genet Mol Res. 2013 Dec 19;12(4):6947-56. doi: 10.4238/2013.December.19.14. Genet Mol Res. 2013. PMID: 24391043
Nucleotide sequence analysis of these two genes revealed that the pepper TAF10 gene encodes a protein of 103 amino acids that belongs to the TAF10 superfamily. The pepper TAF10 gene was highly expressed in the pericarp and placenta, moderately expressed in th …
Nucleotide sequence analysis of these two genes revealed that the pepper TAF10 gene encodes a protein of 103 amino acids that belongs …
73 results