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CRISPR-assisted detection of RNA-protein interactions in living cells.
Yi W, Li J, Zhu X, Wang X, Fan L, Sun W, Liao L, Zhang J, Li X, Ye J, Chen F, Taipale J, Chan KM, Zhang L, Yan J. Yi W, et al. Among authors: taipale j. Nat Methods. 2020 Jul;17(7):685-688. doi: 10.1038/s41592-020-0866-0. Epub 2020 Jun 22. Nat Methods. 2020. PMID: 32572232
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding.
Huang Q, Whitington T, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J, Wei GH. Huang Q, et al. Among authors: taipale j. Nat Genet. 2014 Feb;46(2):126-35. doi: 10.1038/ng.2862. Epub 2014 Jan 5. Nat Genet. 2014. PMID: 24390282
The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.
Liu NQ, Ter Huurne M, Nguyen LN, Peng T, Wang SY, Studd JB, Joshi O, Ongen H, Bramsen JB, Yan J, Andersen CL, Taipale J, Dermitzakis ET, Houlston RS, Hubner NC, Stunnenberg HG. Liu NQ, et al. Among authors: taipale j. Nat Commun. 2017 Feb 14;8:14418. doi: 10.1038/ncomms14418. Nat Commun. 2017. PMID: 28195176 Free PMC article.
CRISPR/Cas9 screening using unique molecular identifiers.
Schmierer B, Botla SK, Zhang J, Turunen M, Kivioja T, Taipale J. Schmierer B, et al. Among authors: taipale j. Mol Syst Biol. 2017 Oct 9;13(10):945. doi: 10.15252/msb.20177834. Mol Syst Biol. 2017. PMID: 28993443 Free PMC article.
The interaction landscape between transcription factors and the nucleosome.
Zhu F, Farnung L, Kaasinen E, Sahu B, Yin Y, Wei B, Dodonova SO, Nitta KR, Morgunova E, Taipale M, Cramer P, Taipale J. Zhu F, et al. Among authors: taipale m, taipale j. Nature. 2018 Oct;562(7725):76-81. doi: 10.1038/s41586-018-0549-5. Epub 2018 Sep 24. Nature. 2018. PMID: 30250250 Free PMC article.
Reply to "CRISPR screens are feasible in TP53 wild-type cells".
Haapaniemi E, Botla S, Persson J, Schmierer B, Taipale J. Haapaniemi E, et al. Among authors: taipale j. Mol Syst Biol. 2019 Aug;15(8):e9059. doi: 10.15252/msb.20199059. Mol Syst Biol. 2019. PMID: 31464368 Free PMC article.
149 results