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Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease.
Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, Muñoz FJ. Tajes M, et al. J Alzheimers Dis. 2014;41(1):273-88. doi: 10.3233/JAD-131685. J Alzheimers Dis. 2014. PMID: 24614897
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells.
Ill-Raga G, Ramos-Fernández E, Guix FX, Tajes M, Bosch-Morató M, Palomer E, Godoy J, Belmar S, Cerpa W, Simpkins JW, Inestrosa And NC, Muñoz FJ. Ill-Raga G, et al. Among authors: tajes m. J Alzheimers Dis. 2010;22(2):641-52. doi: 10.3233/JAD-2010-100474. J Alzheimers Dis. 2010. PMID: 20858976
Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.
Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ. Ill-Raga G, et al. Among authors: tajes m. PLoS One. 2011;6(6):e21456. doi: 10.1371/journal.pone.0021456. Epub 2011 Jun 28. PLoS One. 2011. PMID: 21738672 Free PMC article.
Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death.
Tajes M, Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Galán AM, Alameda F, Escolar G, Opazo C, Planas A, Roquer J, Valverde MA, Muñoz FJ. Tajes M, et al. Oxid Med Cell Longev. 2013;2013:826143. doi: 10.1155/2013/826143. Epub 2013 Aug 1. Oxid Med Cell Longev. 2013. PMID: 23983901 Free PMC article.
Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation.
Ramos-Fernández E, Tajes M, Palomer E, Ill-Raga G, Bosch-Morató M, Guivernau B, Román-Dégano I, Eraso-Pichot A, Alcolea D, Fortea J, Nuñez L, Paez A, Alameda F, Fernández-Busquets X, Lleó A, Elosúa R, Boada M, Valverde MA, Muñoz FJ. Ramos-Fernández E, et al. Among authors: tajes m. J Alzheimers Dis. 2014;40(3):643-57. doi: 10.3233/JAD-130914. J Alzheimers Dis. 2014. PMID: 24503620
Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death.
Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Tajes M, Valls-Comamala V, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Gil-Gómez G, Lopez-Vilchez I, Galan AM, Alameda F, Escolar G, Opazo C, Planas AM, Roquer J, Valverde MA, Muñoz FJ. Ill-Raga G, et al. Among authors: tajes m. Biochim Biophys Acta. 2015 Mar;1852(3):421-8. doi: 10.1016/j.bbadis.2014.12.007. Epub 2014 Dec 12. Biochim Biophys Acta. 2015. PMID: 25500153 Free article.
Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis.
Ill-Raga G, Tajes M, Busquets-García A, Ramos-Fernández E, Vargas LM, Bosch-Morató M, Guivernau B, Valls-Comamala V, Eraso-Pichot A, Guix FX, Fandos C, Rosen MD, Rabinowitz MH, Maldonado R, Alvarez AR, Ozaita A, Muñoz FJ. Ill-Raga G, et al. Among authors: tajes m. Antioxid Redox Signal. 2015 May 20;22(15):1295-307. doi: 10.1089/ars.2014.6080. Epub 2015 Mar 25. Antioxid Redox Signal. 2015. PMID: 25706765
The antigen-binding fragment of human gamma immunoglobulin prevents amyloid β-peptide folding into β-sheet to form oligomers.
Valls-Comamala V, Guivernau B, Bonet J, Puig M, Perálvarez-Marín A, Palomer E, Fernàndez-Busquets X, Altafaj X, Tajes M, Puig-Pijoan A, Vicente R, Oliva B, Muñoz FJ. Valls-Comamala V, et al. Among authors: tajes m. Oncotarget. 2017 Jun 20;8(25):41154-41165. doi: 10.18632/oncotarget.17074. Oncotarget. 2017. PMID: 28467807 Free PMC article.
47 results