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Structure and engineering of the minimal type VI CRISPR-Cas13bt3.
Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K, Zhang F, Nishimasu H, Nureki O. Nakagawa R, et al. Among authors: takeda sn. Mol Cell. 2022 Sep 1;82(17):3178-3192.e5. doi: 10.1016/j.molcel.2022.08.001. Epub 2022 Aug 25. Mol Cell. 2022. PMID: 36027912 Free PMC article.
Structure of the miniature type V-F CRISPR-Cas effector enzyme.
Takeda SN, Nakagawa R, Okazaki S, Hirano H, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K, Nishimasu H, Nureki O. Takeda SN, et al. Mol Cell. 2021 Feb 4;81(3):558-570.e3. doi: 10.1016/j.molcel.2020.11.035. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333018 Free article.
An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.
Hino T, Omura SN, Nakagawa R, Togashi T, Takeda SN, Hiramoto T, Tasaka S, Hirano H, Tokuyama T, Uosaki H, Ishiguro S, Kagieva M, Yamano H, Ozaki Y, Motooka D, Mori H, Kirita Y, Kise Y, Itoh Y, Matoba S, Aburatani H, Yachie N, Karvelis T, Siksnys V, Ohmori T, Hoshino A, Nureki O. Hino T, et al. Among authors: takeda sn. Cell. 2023 Oct 26;186(22):4920-4935.e23. doi: 10.1016/j.cell.2023.08.031. Epub 2023 Sep 29. Cell. 2023. PMID: 37776859 Free article.