Tan W - Search Results

1

A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC.

Lai JC, Tan W, Benimetskaya L, Miller P, Colombini M, Stein CA. Lai JC, et al. Among authors: tan w. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7494-9. doi: 10.1073/pnas.0602217103. Epub 2006 Apr 28. Proc Natl Acad Sci U S A. 2006. PMID: 16648253 Free PMC article.

2

Comparison of d-g3139 and its enantiomer L-g3139 in melanoma cells demonstrates minimal in vitro but dramatic in vivo chiral dependency.

Lai JC, Brown BD, Voskresenskiy AM, Vonhoff S, Klussman S, Tan W, Colombini M, Weeratna R, Miller P, Benimetskaya L, Stein CA. Lai JC, et al. Among authors: tan w. Mol Ther. 2007 Feb;15(2):270-8. doi: 10.1038/sj.mt.6300037. Mol Ther. 2007. PMID: 17235304 Free article.

3

On the role of VDAC in apoptosis: fact and fiction.

Rostovtseva TK, Tan W, Colombini M. Rostovtseva TK, et al. Among authors: tan w. J Bioenerg Biomembr. 2005 Jun;37(3):129-42. doi: 10.1007/s10863-005-6566-8. J Bioenerg Biomembr. 2005. PMID: 16167170

4

Phosphorothioate oligonucleotides reduce mitochondrial outer membrane permeability to ADP.

Tan W, Lai JC, Miller P, Stein CA, Colombini M. Tan W, et al. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1388-97. doi: 10.1152/ajpcell.00490.2006. Epub 2006 Nov 29. Am J Physiol Cell Physiol. 2007. PMID: 17135295 Free article.

5

Phosphorothioate oligonucleotides block the VDAC channel.

Tan W, Loke YH, Stein CA, Miller P, Colombini M. Tan W, et al. Biophys J. 2007 Aug 15;93(4):1184-91. doi: 10.1529/biophysj.107.105379. Epub 2007 May 4. Biophys J. 2007. PMID: 17483171 Free PMC article.

6

VDAC closure increases calcium ion flux.

Tan W, Colombini M. Tan W, et al. Biochim Biophys Acta. 2007 Oct;1768(10):2510-5. doi: 10.1016/j.bbamem.2007.06.002. Epub 2007 Jun 12. Biochim Biophys Acta. 2007. PMID: 17617374 Free PMC article.

7

Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells.

Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Head SA, et al. Among authors: tan w. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7276-85. doi: 10.1073/pnas.1512867112. Epub 2015 Dec 10. Proc Natl Acad Sci U S A. 2015. PMID: 26655341 Free PMC article.

8

Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels.

Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hardwick JM, Colombini M. Siskind LJ, et al. Among authors: tan w. J Biol Chem. 2008 Mar 14;283(11):6622-30. doi: 10.1074/jbc.M706115200. Epub 2008 Jan 2. J Biol Chem. 2008. PMID: 18171672 Free PMC article.

9

VDAC blockage by phosphorothioate oligonucleotides and its implication in apoptosis.

Tan W. Tan W. Biochim Biophys Acta. 2012 Jun;1818(6):1555-61. doi: 10.1016/j.bbamem.2011.12.032. Epub 2012 Jan 4. Biochim Biophys Acta. 2012. PMID: 22236836 Free article. Review.

10

Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.

Wen X, Tan W, Westergard T, Krishnamurthy K, Markandaiah SS, Shi Y, Lin S, Shneider NA, Monaghan J, Pandey UB, Pasinelli P, Ichida JK, Trotti D. Wen X, et al. Among authors: tan w. Neuron. 2014 Dec 17;84(6):1213-25. doi: 10.1016/j.neuron.2014.12.010. Neuron. 2014. PMID: 25521377 Free PMC article.

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