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PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma.
Tan X, Banerjee P, Pham EA, Rutaganira FUN, Basu K, Bota-Rabassedas N, Guo HF, Grzeskowiak CL, Liu X, Yu J, Shi L, Peng DH, Rodriguez BL, Zhang J, Zheng V, Duose DY, Solis LM, Mino B, Raso MG, Behrens C, Wistuba II, Scott KL, Smith M, Nguyen K, Lam G, Choong I, Mazumdar A, Hill JL, Gibbons DL, Brown PH, Russell WK, Shokat K, Creighton CJ, Glenn JS, Kurie JM. Tan X, et al. Sci Transl Med. 2020 Jan 22;12(527):eaax3772. doi: 10.1126/scitranslmed.aax3772. Sci Transl Med. 2020. PMID: 31969487 Free PMC article.
ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, Ungewiss C, Peng DH, Liu X, Lin SH, Thilaganathan N, Wistuba II, Rodriguez-Canales J, McLendon G, Creighton CJ, Kurie JM. Yang Y, et al. Among authors: tan x. J Clin Invest. 2014 Jun;124(6):2696-708. doi: 10.1172/JCI72171. Epub 2014 Apr 24. J Clin Invest. 2014. PMID: 24762440 Free PMC article.
Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Guo HF, Tsai CL, Terajima M, Tan X, Banerjee P, Miller MD, Liu X, Yu J, Byemerwa J, Alvarado S, Kaoud TS, Dalby KN, Bota-Rabassedas N, Chen Y, Yamauchi M, Tainer JA, Phillips GN Jr, Kurie JM. Guo HF, et al. Among authors: tan x. Nat Commun. 2018 Feb 6;9(1):512. doi: 10.1038/s41467-018-02859-z. Nat Commun. 2018. PMID: 29410444 Free PMC article.
The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.
Tan X, Banerjee P, Liu X, Yu J, Gibbons DL, Wu P, Scott KL, Diao L, Zheng X, Wang J, Jalali A, Suraokar M, Fujimoto J, Behrens C, Liu X, Liu CG, Creighton CJ, Wistuba II, Kurie JM. Tan X, et al. J Clin Invest. 2018 Jul 2;128(7):3198. doi: 10.1172/JCI122740. Epub 2018 Jul 2. J Clin Invest. 2018. PMID: 30108197 Free PMC article. No abstract available.
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice.
Guo HF, Bota-Rabassedas N, Terajima M, Leticia Rodriguez B, Gibbons DL, Chen Y, Banerjee P, Tsai CL, Tan X, Liu X, Yu J, Tokmina-Roszyk M, Stawikowska R, Fields GB, Miller MD, Wang X, Lee J, Dalby KN, Creighton CJ, Phillips GN Jr, Tainer JA, Yamauchi M, Kurie JM. Guo HF, et al. Among authors: tan x. Commun Biol. 2021 Apr 19;4(1):482. doi: 10.1038/s42003-021-01982-w. Commun Biol. 2021. PMID: 33875777 Free PMC article.
8,517 results