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A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes.
Ando H, Yoshinaga T, Yamamoto W, Asakura K, Uda T, Taniguchi T, Ojima A, Shinkyo R, Kikuchi K, Osada T, Hayashi S, Kasai C, Miyamoto N, Tashibu H, Yamazaki D, Sugiyama A, Kanda Y, Sawada K, Sekino Y. Ando H, et al. Among authors: taniguchi t. J Pharmacol Toxicol Methods. 2017 Mar-Apr;84:111-127. doi: 10.1016/j.vascn.2016.12.003. Epub 2016 Dec 10. J Pharmacol Toxicol Methods. 2017. PMID: 27956204 Free article.
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes.
Asakura K, Hayashi S, Ojima A, Taniguchi T, Miyamoto N, Nakamori C, Nagasawa C, Kitamura T, Osada T, Honda Y, Kasai C, Ando H, Kanda Y, Sekino Y, Sawada K. Asakura K, et al. Among authors: taniguchi t. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:17-26. doi: 10.1016/j.vascn.2015.04.002. Epub 2015 Apr 22. J Pharmacol Toxicol Methods. 2015. PMID: 25910965 Free article.
Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential.
Yamamoto W, Asakura K, Ando H, Taniguchi T, Ojima A, Uda T, Osada T, Hayashi S, Kasai C, Miyamoto N, Tashibu H, Yoshinaga T, Yamazaki D, Sugiyama A, Kanda Y, Sawada K, Sekino Y. Yamamoto W, et al. Among authors: taniguchi t. PLoS One. 2016 Dec 6;11(12):e0167348. doi: 10.1371/journal.pone.0167348. eCollection 2016. PLoS One. 2016. PMID: 27923051 Free PMC article.
CSAHi study: Detection of drug-induced ion channel/receptor responses, QT prolongation, and arrhythmia using multi-electrode arrays in combination with human induced pluripotent stem cell-derived cardiomyocytes.
Kitaguchi T, Moriyama Y, Taniguchi T, Maeda S, Ando H, Uda T, Otabe K, Oguchi M, Shimizu S, Saito H, Toratani A, Asayama M, Yamamoto W, Matsumoto E, Saji D, Ohnaka H, Miyamoto N. Kitaguchi T, et al. Among authors: taniguchi t. J Pharmacol Toxicol Methods. 2017 May-Jun;85:73-81. doi: 10.1016/j.vascn.2017.02.001. Epub 2017 Feb 3. J Pharmacol Toxicol Methods. 2017. PMID: 28163191
[QT interval shortening].
Taniguchi T, Sawada K. Taniguchi T, et al. Nihon Yakurigaku Zasshi. 2010 Apr;135(4):169-70. Nihon Yakurigaku Zasshi. 2010. PMID: 20429143 Japanese. No abstract available.
CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia--effects of 7 reference compounds at 10 facilities.
Kitaguchi T, Moriyama Y, Taniguchi T, Ojima A, Ando H, Uda T, Otabe K, Oguchi M, Shimizu S, Saito H, Morita M, Toratani A, Asayama M, Yamamoto W, Matsumoto E, Saji D, Ohnaka H, Tanaka K, Washio I, Miyamoto N. Kitaguchi T, et al. Among authors: taniguchi t. J Pharmacol Toxicol Methods. 2016 Mar-Apr;78:93-102. doi: 10.1016/j.vascn.2015.12.002. Epub 2015 Dec 4. J Pharmacol Toxicol Methods. 2016. PMID: 26657830
4,347 results