Immunohistochemical evidence of down-regulation of mu-opioid receptor after chronic PL-017 in rats.
Tao PL, Han KF, Wang SD, Lue WM, Elde R, Law PY, Loh HH.
Tao PL, et al.
Eur J Pharmacol. 1998 Mar 5;344(2-3):137-42. doi: 10.1016/s0014-2999(97)01596-3.
Eur J Pharmacol. 1998.
PMID: 9600647
In a previous study, mu-opioid receptor binding was decreased by chronic treatment of rats with a mu-opioid receptor-selective agonist [CH3Phe3, D-Pro4]morphiceptin (PL-017) [Tao, P.L., Lee, H.Y., Chang, L.R., Loh, H.H., 1990. Decrease in mu-opioid receptor binding …
In a previous study, mu-opioid receptor binding was decreased by chronic treatment of rats with a mu-opioid receptor-selective agonist [CH3P …