Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A.
Kurazono H, Mochida S, Binz T, Eisel U, Quanz M, Grebenstein O, Wernars K, Poulain B, Tauc L, Niemann H.
Kurazono H, et al. Among authors: tauc l.
J Biol Chem. 1992 Jul 25;267(21):14721-9.
J Biol Chem. 1992.
PMID: 1634516
Free article.
Each of the L chains contains a conserved motif, HExxHxxH, characteristic for metalloproteases. ...This finding suggests that the HC domain of the H chain becomes exposed to the cytosol during or after the putative translocation step of the L chain....
Each of the L chains contains a conserved motif, HExxHxxH, characteristic for metalloproteases. ...This finding suggests that the HC …