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Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites.
Du Y, Chang W, Gao L, Deng L, Ji WK. Du Y, et al. J Cell Biol. 2023 Apr 3;222(4):e202205133. doi: 10.1083/jcb.202205133. Epub 2023 Jan 27. J Cell Biol. 2023. PMID: 36705603 Free PMC article.
We show that the Tex2-TMEM55 interaction occurs between an N-terminal region of Tex2 and a catalytic motif in the PTase domain of TMEM55. The Tex2-TMEM55 interaction can be regulated by endosome-resident type 2 PI4K activities. ...
We show that the Tex2-TMEM55 interaction occurs between an N-terminal region of Tex2 and a catalytic motif in the PTase domain …
Circ_TEX2 Functions as a Tumor Suppressor in Hepatoma via miR-96-5p/SPRED1 Axis.
Yuan Q, Zhang Y, Li J, Zhang D, Yang W. Yuan Q, et al. Mol Biotechnol. 2023 Oct;65(10):1679-1692. doi: 10.1007/s12033-023-00669-3. Epub 2023 Feb 6. Mol Biotechnol. 2023. PMID: 36745282
Dual-luciferase reporter assay was done to analyze the target relationship between miR-96-5p and circ_TEX2 or SPRED1. The effects of circ_TEX2 on tumor growth in vivo were verified by xenograft model experiment and immunohistochemistry assay. ...Circ_TEX2 cou …
Dual-luciferase reporter assay was done to analyze the target relationship between miR-96-5p and circ_TEX2 or SPRED1. The effects of …
Loss of THIN EXINE2 disrupts multiple processes in the mechanism of pollen exine formation.
Wang R, Dobritsa AA. Wang R, et al. Plant Physiol. 2021 Sep 4;187(1):133-157. doi: 10.1093/plphys/kiab244. Plant Physiol. 2021. PMID: 34618131 Free PMC article.
Here, we characterized an Arabidopsis (Arabidopsis thaliana) mutant, thin exine2 (tex2), which develops pollen with abnormally thin exine. The TEX2 gene (also known as REPRESSOR OF CYTOKININ DEFICIENCY1 (ROCK1)) encodes a putative nucleotide-sugar transporter locali …
Here, we characterized an Arabidopsis (Arabidopsis thaliana) mutant, thin exine2 (tex2), which develops pollen with abnormally thin e …
Two Tabersonine 6,7-Epoxidases Initiate Lochnericine-Derived Alkaloid Biosynthesis in Catharanthus roseus.
Carqueijeiro I, Brown S, Chung K, Dang TT, Walia M, Besseau S, Dugé de Bernonville T, Oudin A, Lanoue A, Billet K, Munsch T, Koudounas K, Melin C, Godon C, Razafimandimby B, de Craene JO, Glévarec G, Marc J, Giglioli-Guivarc'h N, Clastre M, St-Pierre B, Papon N, Andrade RB, O'Connor SE, Courdavault V. Carqueijeiro I, et al. Plant Physiol. 2018 Aug;177(4):1473-1486. doi: 10.1104/pp.18.00549. Epub 2018 Jun 22. Plant Physiol. 2018. PMID: 29934299 Free PMC article.
Biochemical characterization of TEX1/2 revealed their strict substrate specificity for tabersonine and their inability to epoxidize 19-hydroxytabersonine, indicating that they catalyze the first step in the pathway leading to horhammericine production. TEX1 and TEX2 displa …
Biochemical characterization of TEX1/2 revealed their strict substrate specificity for tabersonine and their inability to epoxidize 19-hydro …
The TICE Pathway: Mechanisms and Lipid-Lowering Therapies.
Grefhorst A, Verkade HJ, Groen AK. Grefhorst A, et al. Methodist Debakey Cardiovasc J. 2019 Jan-Mar;15(1):70-76. doi: 10.14797/mdcj-15-1-70. Methodist Debakey Cardiovasc J. 2019. PMID: 31049152 Free PMC article. Review.
Scrutinizing the human TEX genes in the context of human male infertility.
Sieper MH, Gaikwad AS, Fros M, Weber P, Di Persio S, Oud MS, Kliesch S, Neuhaus N, Stallmeyer B, Tüttelmann F, Wyrwoll MJ. Sieper MH, et al. Andrology. 2024 Mar;12(3):570-584. doi: 10.1111/andr.13511. Epub 2023 Aug 18. Andrology. 2024. PMID: 37594251
RESULTS: We detected rare potential disease-causing variants in TEX10, TEX13A, TEX13B, TEX13C, TEX13D, ZFAND3 (TEX27), TEX33, FAM9A (TEX39A), and FAM9B (TEX39B), in 28 infertile men, of which 15 men carried variants in TEX10, TEX27, and TEX33. The KD of TEX2, TEX9, TEX10, …
RESULTS: We detected rare potential disease-causing variants in TEX10, TEX13A, TEX13B, TEX13C, TEX13D, ZFAND3 (TEX27), TEX33, FAM9A (TEX39A) …
Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions.
Kim JH, Megquier K, Thomas R, Sarver AL, Song JM, Kim YT, Cheng N, Schulte AJ, Linden MA, Murugan P, Oseth L, Forster CL, Elvers I, Swofford R, Turner-Maier J, Karlsson EK, Breen M, Lindblad-Toh K, Modiano JF. Kim JH, et al. Mol Cancer Res. 2021 May;19(5):847-861. doi: 10.1158/1541-7786.MCR-20-0937. Epub 2021 Mar 1. Mol Cancer Res. 2021. PMID: 33649193 Free PMC article.
In this study, we leveraged RNA-sequencing data from 13 human angiosarcomas and 76 spontaneous canine hemangiosarcomas to identify fusion genes associated with spontaneous vascular malignancies. Ten novel protein-coding fusion genes, including TEX2-PECAM1 and ATP8A2-FLT1, …
In this study, we leveraged RNA-sequencing data from 13 human angiosarcomas and 76 spontaneous canine hemangiosarcomas to identify fusion ge …
Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI.
Young SW, Qing F, Harriman A, Sessler JL, Dow WC, Mody TD, Hemmi GW, Hao Y, Miller RA. Young SW, et al. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6610-5. doi: 10.1073/pnas.93.13.6610. Proc Natl Acad Sci U S A. 1996. PMID: 8692865 Free PMC article.
Gadolinium(III) texaphyrin (Gd-tex2+) is representative of a new class of radiation sensitizers detectable by magnetic resonance imaging (MRI). ...Selective localization of Gd-tex2+ in tumors was confirmed by MRI scanning....
Gadolinium(III) texaphyrin (Gd-tex2+) is representative of a new class of radiation sensitizers detectable by magnetic resonance imag …
Estimation of direct and maternal genetic effects and annotation of potential candidate genes for weight and meat quality traits in a genotyped outdoor dual-purpose cattle breed.
Halli K, Bohlouli M, Schulz L, Sundrum A, König S. Halli K, et al. Transl Anim Sci. 2022 Feb 3;6(1):txac022. doi: 10.1093/tas/txac022. eCollection 2022 Jan. Transl Anim Sci. 2022. PMID: 35308836 Free PMC article.
Regarding maternal genetic effects, four (SHROOM3, ZNF609, PECAM1, and TEX2) and two (TMEM182 and SEC11A) genes were detected as potential candidate genes for BWT and 365dW, respectively. ...
Regarding maternal genetic effects, four (SHROOM3, ZNF609, PECAM1, and TEX2) and two (TMEM182 and SEC11A) genes were detected as pote …
21 results