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Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes.
Gondry M, Sauguet L, Belin P, Thai R, Amouroux R, Tellier C, Tuphile K, Jacquet M, Braud S, Courçon M, Masson C, Dubois S, Lautru S, Lecoq A, Hashimoto S, Genet R, Pernodet JL. Gondry M, et al. Among authors: thai r. Nat Chem Biol. 2009 Jun;5(6):414-20. doi: 10.1038/nchembio.175. Nat Chem Biol. 2009. PMID: 19430487
Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity.
Canu N, Tellier C, Babin M, Thai R, Ajel I, Seguin J, Cinquin O, Vinck R, Moutiez M, Belin P, Cintrat JC, Gondry M. Canu N, et al. Among authors: thai r. Nucleic Acids Res. 2020 Nov 18;48(20):11615-11625. doi: 10.1093/nar/gkaa903. Nucleic Acids Res. 2020. PMID: 33095883 Free PMC article.
Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.
Belin P, Le Du MH, Fielding A, Lequin O, Jacquet M, Charbonnier JB, Lecoq A, Thai R, Courçon M, Masson C, Dugave C, Genet R, Pernodet JL, Gondry M. Belin P, et al. Among authors: thai r. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7426-31. doi: 10.1073/pnas.0812191106. Epub 2009 Apr 22. Proc Natl Acad Sci U S A. 2009. PMID: 19416919 Free PMC article.
65 results