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Page 1
Cannabinergic ligands.
Palmer SL, Thakur GA, Makriyannis A. Palmer SL, et al. Among authors: thakur ga. Chem Phys Lipids. 2002 Dec 31;121(1-2):3-19. doi: 10.1016/s0009-3084(02)00143-3. Chem Phys Lipids. 2002. PMID: 12505686 Review.
Behavioral effects of the novel cannabinoid full agonist AM 411.
McLaughlin PJ, Lu D, Winston KM, Thakur G, Swezey LA, Makriyannis A, Salamone JD. McLaughlin PJ, et al. Pharmacol Biochem Behav. 2005 May;81(1):78-88. doi: 10.1016/j.pbb.2005.02.005. Epub 2005 Apr 21. Pharmacol Biochem Behav. 2005. PMID: 15894067
Adamantyl cannabinoids: a novel class of cannabinergic ligands.
Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Lu D, et al. Among authors: thakur ga. J Med Chem. 2005 Jul 14;48(14):4576-85. doi: 10.1021/jm058175c. J Med Chem. 2005. PMID: 15999995
CB1 cannabinoid receptor ligands.
Thakur GA, Nikas SP, Makriyannis A. Thakur GA, et al. Mini Rev Med Chem. 2005 Jul;5(7):631-40. doi: 10.2174/1389557054368772. Mini Rev Med Chem. 2005. PMID: 16026309 Review.
(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor.
Picone RP, Khanolkar AD, Xu W, Ayotte LA, Thakur GA, Hurst DP, Abood ME, Reggio PH, Fournier DJ, Makriyannis A. Picone RP, et al. Among authors: thakur ga. Mol Pharmacol. 2005 Dec;68(6):1623-35. doi: 10.1124/mol.105.014407. Epub 2005 Sep 12. Mol Pharmacol. 2005. PMID: 16157695
Natural cannabinoids: templates for drug discovery.
Thakur GA, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Life Sci. 2005 Dec 22;78(5):454-66. doi: 10.1016/j.lfs.2005.09.014. Epub 2005 Oct 19. Life Sci. 2005. PMID: 16242157 Review.
Methods for the synthesis of cannabinergic ligands.
Thakur GA, Nikas SP, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Methods Mol Med. 2006;123:113-48. doi: 10.1385/1-59259-999-0:113. Methods Mol Med. 2006. PMID: 16506405
133 results