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Humanized hemato-lymphoid system mice.
Theocharides AP, Rongvaux A, Fritsch K, Flavell RA, Manz MG. Theocharides AP, et al. Haematologica. 2016 Jan;101(1):5-19. doi: 10.3324/haematol.2014.115212. Haematologica. 2016. PMID: 26721800 Free PMC article. Review.
PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy.
Maru B, Messikommer A, Huang L, Seipel K, Kovecses O, Valk PJM, Theocharides APA, Mercier FE, Pabst T, McKeague M, Luedtke NW. Maru B, et al. Among authors: theocharides apa. Cell Rep Med. 2023 Sep 19;4(9):101191. doi: 10.1016/j.xcrm.2023.101191. Epub 2023 Sep 7. Cell Rep Med. 2023. PMID: 37683650 Free PMC article.
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Grockowiak E, Korn C, Rak J, Lysenko V, Hallou A, Panvini FM, Williams M, Fielding C, Fang Z, Khatib-Massalha E, García-García A, Li J, Khorshed RA, González-Antón S, Baxter EJ, Kusumbe A, Wilkins BS, Green A, Simons BD, Harrison CN, Green AR, Lo Celso C, Theocharides APA, Méndez-Ferrer S. Grockowiak E, et al. Among authors: theocharides apa. Nat Cancer. 2023 Aug;4(8):1193-1209. doi: 10.1038/s43018-023-00607-x. Epub 2023 Aug 7. Nat Cancer. 2023. PMID: 37550517 Free PMC article.
Bone marrow haematopoiesis in patients with COVID-19.
Marques-Maggio E, Maccio U, Marx A, Galli S, Schwab N, Frank A, Hamelin B, Varga Z, Nombela-Arrieta C, Mertz KD, Theocharides AP, Koelzer VH. Marques-Maggio E, et al. Among authors: theocharides ap. Histopathology. 2023 Oct;83(4):582-590. doi: 10.1111/his.14969. Epub 2023 Jun 14. Histopathology. 2023. PMID: 37317636
IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.
Mager LF, Riether C, Schürch CM, Banz Y, Wasmer MH, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, Nakae S, Baerlocher GM, Manz MG, McCoy KD, Macpherson AJ, Ochsenbein AF, Beutler B, Krebs P. Mager LF, et al. Among authors: theocharides ap. J Clin Invest. 2015 Jul 1;125(7):2579-91. doi: 10.1172/JCI77347. Epub 2015 May 26. J Clin Invest. 2015. PMID: 26011644 Free PMC article.
inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice.
Ellegast JM, Rauch PJ, Kovtonyuk LV, Müller R, Wagner U, Saito Y, Wildner-Verhey van Wijk N, Fritz C, Rafiei A, Lysenko V, Dudkiewicz E, Theocharides AP, Soldini D, Goede JS, Flavell RA, Manz MG. Ellegast JM, et al. Among authors: theocharides ap. Blood. 2016 Oct 27;128(17):2130-2134. doi: 10.1182/blood-2015-12-689356. Epub 2016 Aug 31. Blood. 2016. PMID: 27581357 Free PMC article.
Humanised mouse models for haematopoiesis and infectious diseases.
Lysenko V, McHugh D, Behrmann L, Rochat MA, Wilk CM, Kovtonyuk L, Bourquin JP, Münz C, Manz MG, Speck R, Theocharides A. Lysenko V, et al. Swiss Med Wkly. 2017 Oct 22;147:w14516. doi: 10.4414/smw.2017.14516. eCollection 2017. Swiss Med Wkly. 2017. PMID: 29120027 Free article. Review.
Finally: development of humanized lymph nodes.
Theocharides APA, Manz MG. Theocharides APA, et al. Nat Methods. 2018 Aug;15(8):580-582. doi: 10.1038/s41592-018-0080-5. Nat Methods. 2018. PMID: 30065374 No abstract available.
The sympathomimetic agonist mirabegron did not lower JAK2-V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with myeloproliferative neoplasms: results of phase II study SAKK 33/14.
Drexler B, Passweg JR, Tzankov A, Bigler M, Theocharides AP, Cantoni N, Keller P, Stussi G, Ruefer A, Benz R, Favre G, Lundberg P, Nienhold R, Fuhrer A, Biaggi C, Manz MG, Bargetzi M, Mendez-Ferrer S, Skoda RC; Swiss Group for Clinical Cancer Research (SAKK). Drexler B, et al. Among authors: theocharides ap. Haematologica. 2019 Apr;104(4):710-716. doi: 10.3324/haematol.2018.200014. Epub 2018 Nov 8. Haematologica. 2019. PMID: 30409796 Free PMC article. Clinical Trial.
49 results