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Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.
Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P. Ng KP, et al. Among authors: therriault j. Alzheimers Res Ther. 2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y. Alzheimers Res Ther. 2017. PMID: 28359327 Free PMC article.
Anosognosia predicts default mode network hypometabolism and clinical progression to dementia.
Therriault J, Ng KP, Pascoal TA, Mathotaarachchi S, Kang MS, Struyfs H, Shin M, Benedet AL, Walpola IC, Nair V, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Therriault J, et al. Neurology. 2018 Mar 13;90(11):e932-e939. doi: 10.1212/WNL.0000000000005120. Epub 2018 Feb 14. Neurology. 2018. PMID: 29444971 Free PMC article.
In vivo quantification of neurofibrillary tangles with [18F]MK-6240.
Pascoal TA, Shin M, Kang MS, Chamoun M, Chartrand D, Mathotaarachchi S, Bennacef I, Therriault J, Ng KP, Hopewell R, Bouhachi R, Hsiao HH, Benedet AL, Soucy JP, Massarweh G, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Among authors: therriault j. Alzheimers Res Ther. 2018 Jul 31;10(1):74. doi: 10.1186/s13195-018-0402-y. Alzheimers Res Ther. 2018. PMID: 30064520 Free PMC article.
Cerebrospinal fluid phosphorylated tau, visinin-like protein-1, and chitinase-3-like protein 1 in mild cognitive impairment and Alzheimer's disease.
Zhang H, Ng KP, Therriault J, Kang MS, Pascoal TA, Rosa-Neto P, Gauthier S; Alzheimer’s Disease Neuroimaging Initiative. Zhang H, et al. Among authors: therriault j. Transl Neurodegener. 2018 Sep 10;7:23. doi: 10.1186/s40035-018-0127-7. eCollection 2018. Transl Neurodegener. 2018. PMID: 30311914 Free PMC article.
Aβ-induced vulnerability propagates via the brain's default mode network.
Pascoal TA, Mathotaarachchi S, Kang MS, Mohaddes S, Shin M, Park AY, Parent MJ, Benedet AL, Chamoun M, Therriault J, Hwang H, Cuello AC, Misic B, Soucy JP, Aston JAD, Gauthier S, Rosa-Neto P. Pascoal TA, et al. Among authors: therriault j. Nat Commun. 2019 Jun 4;10(1):2353. doi: 10.1038/s41467-019-10217-w. Nat Commun. 2019. PMID: 31164641 Free PMC article.
Rostral-Caudal Hippocampal Functional Convergence Is Reduced Across the Alzheimer's Disease Spectrum.
Therriault J, Wang S, Mathotaarachchi S, Pascoal TA, Parent M, Beaudry T, Shin M, Al B, Kang MS, Ng KP, Dansereau C, Park MTM, Fonov V, Carbonell F, Zimmer E, Chakravarty MM, Bellec P, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Therriault J, et al. Mol Neurobiol. 2019 Dec;56(12):8336-8344. doi: 10.1007/s12035-019-01671-0. Epub 2019 Jun 22. Mol Neurobiol. 2019. PMID: 31230260
Suicidal ideation is common in autosomal dominant Alzheimer's disease at-risk persons.
Ng KP, Richard-Devantoy S, Bertrand JA, Jiang L, Pascoal TA, Mathotaarachchi S, Therriault J, Yatawara C, Kandiah N, Greenwood CMT, Rosa-Neto P, Gauthier S; Dominantly Inherited Alzheimer Network. Ng KP, et al. Among authors: therriault j. Int J Geriatr Psychiatry. 2020 Jan;35(1):60-68. doi: 10.1002/gps.5215. Epub 2019 Oct 22. Int J Geriatr Psychiatry. 2020. PMID: 31642105 Free PMC article.
Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals.
Benedet AL, Ashton NJ, Pascoal TA, Leuzy A, Mathotaarachchi S, Kang MS, Therriault J, Savard M, Chamoun M, Schöll M, Zimmer ER, Gauthier S, Labbe A, Zetterberg H, Blennow K, Neto PR. Benedet AL, et al. Among authors: therriault j. Alzheimers Dement (Amst). 2019 Sep 27;11:679-689. doi: 10.1016/j.dadm.2019.08.002. eCollection 2019 Dec. Alzheimers Dement (Amst). 2019. PMID: 31673598 Free PMC article.
109 results