Thiagarajah JR - Search Results

1

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, Verkman AS. Ma T, et al. Among authors: thiagarajah jr. J Clin Invest. 2002 Dec;110(11):1651-8. doi: 10.1172/JCI16112. J Clin Invest. 2002. PMID: 12464670 Free PMC article.

2

In vivo fluorescence measurement of Na(+) concentration in the pericryptal space of mouse descending colon.

Thiagarajah JR, Jayaraman S, Naftalin RJ, Verkman AS. Thiagarajah JR, et al. Am J Physiol Cell Physiol. 2001 Dec;281(6):C1898-903. doi: 10.1152/ajpcell.2001.281.6.C1898. Am J Physiol Cell Physiol. 2001. PMID: 11698248 Free article.

3

Chloride concentration in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidification.

Sonawane ND, Thiagarajah JR, Verkman AS. Sonawane ND, et al. Among authors: thiagarajah jr. J Biol Chem. 2002 Feb 15;277(7):5506-13. doi: 10.1074/jbc.M110818200. Epub 2001 Dec 7. J Biol Chem. 2002. PMID: 11741919 Free article.

4

Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling.

Thiagarajah JR, Verkman AS. Thiagarajah JR, et al. J Biol Chem. 2002 May 24;277(21):19139-44. doi: 10.1074/jbc.M202071200. Epub 2002 Mar 12. J Biol Chem. 2002. PMID: 11891232 Free article.

5

Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease.

Verkman AS, Song Y, Thiagarajah JR. Verkman AS, et al. Among authors: thiagarajah jr. Am J Physiol Cell Physiol. 2003 Jan;284(1):C2-15. doi: 10.1152/ajpcell.00417.2002. Am J Physiol Cell Physiol. 2003. PMID: 12475759 Free article. Review.

6

Sodium and chloride concentrations, pH, and depth of airway surface liquid in distal airways.

Song Y, Thiagarajah J, Verkman AS. Song Y, et al. J Gen Physiol. 2003 Nov;122(5):511-9. doi: 10.1085/jgp.200308866. Epub 2003 Oct 13. J Gen Physiol. 2003. PMID: 14557401 Free PMC article.

7

CFTR pharmacology and its role in intestinal fluid secretion.

Thiagarajah JR, Verkman AS. Thiagarajah JR, et al. Curr Opin Pharmacol. 2003 Dec;3(6):594-9. doi: 10.1016/j.coph.2003.06.012. Curr Opin Pharmacol. 2003. PMID: 14644010 Review.

8

Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor.

Thiagarajah JR, Broadbent T, Hsieh E, Verkman AS. Thiagarajah JR, et al. Gastroenterology. 2004 Feb;126(2):511-9. doi: 10.1053/j.gastro.2003.11.005. Gastroenterology. 2004. PMID: 14762788

9

A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways.

Thiagarajah JR, Song Y, Haggie PM, Verkman AS. Thiagarajah JR, et al. FASEB J. 2004 May;18(7):875-7. doi: 10.1096/fj.03-1248fje. Epub 2004 Mar 4. FASEB J. 2004. PMID: 15001557

10

Submucosal gland dysfunction as a primary defect in cystic fibrosis.

Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson DW, Verkman AS. Salinas D, et al. Among authors: thiagarajah jr. FASEB J. 2005 Mar;19(3):431-3. doi: 10.1096/fj.04-2879fje. Epub 2004 Dec 13. FASEB J. 2005. PMID: 15596485

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