Thompson LM - Search Results

1

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.

Ochaba J, Monteys AM, O'Rourke JG, Reidling JC, Steffan JS, Davidson BL, Thompson LM. Ochaba J, et al. Among authors: thompson lm. Neuron. 2016 May 4;90(3):507-20. doi: 10.1016/j.neuron.2016.03.016. Epub 2016 Apr 14. Neuron. 2016. PMID: 27146268 Free PMC article.

2

Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae.

Thompson LM, Sutherland P, Steffan JS, McAlister-Henn L. Thompson LM, et al. Biochemistry. 1988 Nov 1;27(22):8393-400. doi: 10.1021/bi00422a015. Biochemistry. 1988. PMID: 3072021

3

Modeling protein homopolymeric repeats: possible polyglutamine structural motifs for Huntington's disease.

Lathrop RH, Casale M, Tobias DJ, Marsh JL, Thompson LM. Lathrop RH, et al. Among authors: thompson lm. Proc Int Conf Intell Syst Mol Biol. 1998;6:105-14. Proc Int Conf Intell Syst Mol Biol. 1998. PMID: 9783215

4

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6763-8. doi: 10.1073/pnas.100110097. Proc Natl Acad Sci U S A. 2000. PMID: 10823891 Free PMC article.

5

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Nature. 2001 Oct 18;413(6857):739-43. doi: 10.1038/35099568. Nature. 2001. PMID: 11607033

6

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila.

Kazantsev A, Walker HA, Slepko N, Bear JE, Preisinger E, Steffan JS, Zhu YZ, Gertler FB, Housman DE, Marsh JL, Thompson LM. Kazantsev A, et al. Among authors: thompson lm. Nat Genet. 2002 Apr;30(4):367-76. doi: 10.1038/ng864. Epub 2002 Mar 25. Nat Genet. 2002. PMID: 11925563

7

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.

Hockly E, Richon VM, Woodman B, Smith DL, Zhou X, Rosa E, Sathasivam K, Ghazi-Noori S, Mahal A, Lowden PA, Steffan JS, Marsh JL, Thompson LM, Lewis CM, Marks PA, Bates GP. Hockly E, et al. Among authors: thompson lm. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2041-6. doi: 10.1073/pnas.0437870100. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576549 Free PMC article.

8

Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases.

Steffan JS, Thompson LM. Steffan JS, et al. Among authors: thompson lm. Expert Opin Ther Targets. 2003 Apr;7(2):201-13. doi: 10.1517/14728222.7.2.201. Expert Opin Ther Targets. 2003. PMID: 12667098 Review.

9

Fly models of Huntington's disease.

Marsh JL, Pallos J, Thompson LM. Marsh JL, et al. Among authors: thompson lm. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R187-93. doi: 10.1093/hmg/ddg271. Epub 2003 Aug 12. Hum Mol Genet. 2003. PMID: 12925571 Review.

10

Autophagy regulates the processing of amino terminal huntingtin fragments.

Qin ZH, Wang Y, Kegel KB, Kazantsev A, Apostol BL, Thompson LM, Yoder J, Aronin N, DiFiglia M. Qin ZH, et al. Among authors: thompson lm. Hum Mol Genet. 2003 Dec 15;12(24):3231-44. doi: 10.1093/hmg/ddg346. Epub 2003 Oct 21. Hum Mol Genet. 2003. PMID: 14570716

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