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Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast.
EMBO J. 2006 Jul 12;25(13):3214-22. doi: 10.1038/sj.emboj.7601189. Epub 2006 Jun 15.
EMBO J. 2006.
PMID: 16778769
Free PMC article.
Apicomplexan parasites contain a single lipoic acid synthase located in the plastid.
Thomsen-Zieger N, Schachtner J, Seeber F.
Thomsen-Zieger N, et al.
FEBS Lett. 2003 Jul 17;547(1-3):80-6. doi: 10.1016/s0014-5793(03)00673-2.
FEBS Lett. 2003.
PMID: 12860390
Free article.
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A single in vivo-selected point mutation in the active center of Toxoplasma gondii ferredoxin-NADP+ reductase leads to an inactive enzyme with greatly enhanced affinity for ferredoxin.
Thomsen-Zieger N, Pandini V, Caprini G, Aliverti A, Cramer J, Selzer PM, Zanetti G, Seeber F.
Thomsen-Zieger N, et al.
FEBS Lett. 2004 Oct 22;576(3):375-80. doi: 10.1016/j.febslet.2004.09.042.
FEBS Lett. 2004.
PMID: 15498566
Free article.
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