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thymus doerfler
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Thymus doerfleri
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Presenilin-dependent gamma-secretase activity modulates thymocyte development.
Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9312-7. doi: 10.1073/pnas.161102498. Epub 2001 Jul 24.
Proc Natl Acad Sci U S A. 2001.
PMID: 11470902
Free PMC article.
Caspase enzyme activity is not essential for apoptosis during thymocyte development.
Doerfler P, Forbush KA, Perlmutter RM.
Doerfler P, et al.
J Immunol. 2000 Apr 15;164(8):4071-9. doi: 10.4049/jimmunol.164.8.4071.
J Immunol. 2000.
PMID: 10754300
To address the importance of caspases in thymocyte development, we have generated transgenic mice that express the baculovirus protein p35, a viral caspase inhibitor, specifically in the thymus. p35 expression inhibited Fas (CD95)-, CD3-, or peptide-induced caspase activit …
To address the importance of caspases in thymocyte development, we have generated transgenic mice that express the baculovirus protein p35, …
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