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DNA-damaging agents induce both p53-dependent and p53-independent apoptosis in immature thymocytes.
MacFarlane M, Jones NA, Dive C, Cohen GM. MacFarlane M, et al. Mol Pharmacol. 1996 Oct;50(4):900-11. Mol Pharmacol. 1996. PMID: 8863836
Apoptosis in the immature thymus can be induced by both p53-dependent and -independent pathways, the former being activated by exposure to DNA-damaging agents and the latter being induced by glucocorticoids [Nature (Lond.) 362:847-849; Nature (Lond.) 362:849-852 (1993)]. W …
Apoptosis in the immature thymus can be induced by both p53-dependent and -independent pathways, the former being activated by exposu …
The limiting conditional probability distribution in a stochastic model of T cell repertoire maintenance.
Stirk ER, Lythe G, van den Berg HA, Hurst GA, Molina-París C. Stirk ER, et al. Math Biosci. 2010 Apr;224(2):74-86. doi: 10.1016/j.mbs.2009.12.004. Epub 2010 Jan 6. Math Biosci. 2010. PMID: 20060005
In this paper we model T cell repertoire maintenance by means of a continuous-time birth and death process on the positive integers, where the origin is an absorbing state. We show that eventual extinction is guaranteed. ...
In this paper we model T cell repertoire maintenance by means of a continuous-time birth and death process on the positive integers, …