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Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 4. Structure-activity relationship in the dihydropyrimidine series.
Wong WC, Sun W, Lagu B, Tian D, Marzabadi MR, Zhang F, Nagarathnam D, Miao SW, Wetzel JM, Peng J, Forray C, Chang RS, Chen TB, Ransom R, O'Malley S, Broten TP, Kling P, Vyas KP, Zhang K, Gluchowski C. Wong WC, et al. Among authors: tian d. J Med Chem. 1999 Nov 18;42(23):4804-13. doi: 10.1021/jm9902032. J Med Chem. 1999. PMID: 10579843
Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 2. Approaches to eliminate opioid agonist metabolites via modification of linker and 4-methoxycarbonyl-4-phenylpiperidine moiety.
Murali Dhar TG, Nagarathnam D, Marzabadi MR, Lagu B, Wong WC, Chiu G, Tyagarajan S, Miao SW, Zhang F, Sun W, Tian D, Shen Q, Zhang J, Wetzel JM, Forray C, Chang RS, Broten TP, Schorn TW, Chen TB, O'Malley S, Ransom R, Schneck K, Bendesky R, Harrell CM, Vyas KP, et al. Murali Dhar TG, et al. Among authors: tian d. J Med Chem. 1999 Nov 18;42(23):4778-93. doi: 10.1021/jm990201h. J Med Chem. 1999. PMID: 10579841
Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 3. Approaches to eliminate opioid agonist metabolites by using substituted phenylpiperazine side chains.
Lagu B, Tian D, Nagarathnam D, Marzabadi MR, Wong WC, Miao SW, Zhang F, Sun W, Chiu G, Fang J, Forray C, Chang RS, Ransom RW, Chen TB, O'Malley S, Zhang K, Vyas KP, Gluchowski C. Lagu B, et al. Among authors: tian d. J Med Chem. 1999 Nov 18;42(23):4794-803. doi: 10.1021/jm990202+. J Med Chem. 1999. PMID: 10579842
Design and synthesis of novel alpha(1)(a) adrenoceptor-selective antagonists. 1. Structure-activity relationship in dihydropyrimidinones.
Nagarathnam D, Miao SW, Lagu B, Chiu G, Fang J, Murali Dhar TG, Zhang J, Tyagarajan S, Marzabadi MR, Zhang F, Wong WC, Sun W, Tian D, Wetzel JM, Forray C, Chang RS, Broten TP, Ransom RW, Schorn TW, Chen TB, O'Malley S, Kling P, Schneck K, Bendesky R, Harrell CM, et al. Nagarathnam D, et al. Among authors: tian d. J Med Chem. 1999 Nov 18;42(23):4764-77. doi: 10.1021/jm990200p. J Med Chem. 1999. PMID: 10579840
De novo design of a novel oxazolidinone analogue as a potent and selective alpha1A adrenergic receptor antagonist with high oral bioavailability.
Lagu B, Tian D, Jeon Y, Li C, Wetzel JM, Nagarathnam D, Shen Q, Forray C, Chang RS, Broten TP, Ransom RW, Chan TB, O'Malley SS, Schorn TW, Rodrigues AD, Kassahun K, Pettibone DJ, Freidinger RO, Gluchowski C. Lagu B, et al. Among authors: tian d. J Med Chem. 2000 Jul 27;43(15):2775-8. doi: 10.1021/jm000085e. J Med Chem. 2000. PMID: 10956183 No abstract available.
3,069 results