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Topotecan is a substrate for multidrug resistance associated protein 4.
Tian Q, Zhang J, Chan SY, Tan TM, Duan W, Huang M, Zhu YZ, Chan E, Yu Q, Nie YQ, Ho PC, Li Q, Ng KY, Yang HY, Wei H, Bian JS, Zhou SF. Tian Q, et al. Curr Drug Metab. 2006 Jan;7(1):105-18. doi: 10.2174/138920006774832550. Curr Drug Metab. 2006. PMID: 16454695
Reversal of resistance to oxazaphosphorines.
Zhang J, Tian Q, Zhu YZ, Xu AL, Zhou SF. Zhang J, et al. Among authors: tian q. Curr Cancer Drug Targets. 2006 Aug;6(5):385-407. doi: 10.2174/156800906777723967. Curr Cancer Drug Targets. 2006. PMID: 16918308 Review.
3,192 results