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POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells.
Schrempf A, Bernardo S, Arasa Verge EA, Ramirez Otero MA, Wilson J, Kirchhofer D, Timelthaler G, Ambros AM, Kaya A, Wieder M, Ecker GF, Winter GE, Costanzo V, Loizou JI. Schrempf A, et al. Among authors: timelthaler g. Cell Rep. 2022 Nov 29;41(9):111716. doi: 10.1016/j.celrep.2022.111716. Epub 2022 Nov 17. Cell Rep. 2022. PMID: 36400033 Free article.
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, Schernthanner M, Bischl R, Herndler-Brandstetter D, Glitzner E, Moll HP, Casanova E, Timelthaler G, Sibilia M, Gnant M, Lax S, Thaler J, Müller M, Strobl B, Mohr T, Kaser A, Trajanoski Z, Heller G, Eferl R. Pflügler S, et al. Among authors: timelthaler g. Commun Biol. 2020 May 22;3(1):252. doi: 10.1038/s42003-020-0989-y. Commun Biol. 2020. PMID: 32444775 Free PMC article.
Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.
Englinger B, Kallus S, Senkiv J, Heilos D, Gabler L, van Schoonhoven S, Terenzi A, Moser P, Pirker C, Timelthaler G, Jäger W, Kowol CR, Heffeter P, Grusch M, Berger W. Englinger B, et al. Among authors: timelthaler g. J Exp Clin Cancer Res. 2017 Sep 7;36(1):122. doi: 10.1186/s13046-017-0592-3. J Exp Clin Cancer Res. 2017. PMID: 28882160 Free PMC article.
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis.
Redl E, Sheibani-Tezerji R, Cardona CJ, Hamminger P, Timelthaler G, Hassler MR, Zrimšek M, Lagger S, Dillinger T, Hofbauer L, Draganić K, Tiefenbacher A, Kothmayer M, Dietz CH, Ramsahoye BH, Kenner L, Bock C, Seiser C, Ellmeier W, Schweikert G, Egger G. Redl E, et al. Among authors: timelthaler g. Life Sci Alliance. 2020 Dec 11;4(2):e202000794. doi: 10.26508/lsa.202000794. Print 2021 Feb. Life Sci Alliance. 2020. PMID: 33310759 Free PMC article.
Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis.
Svinka J, Pflügler S, Mair M, Marschall HU, Hengstler JG, Stiedl P, Poli V, Casanova E, Timelthaler G, Sibilia M, Eferl R. Svinka J, et al. Among authors: timelthaler g. J Mol Med (Berl). 2017 Jan;95(1):109-117. doi: 10.1007/s00109-016-1462-8. Epub 2016 Aug 27. J Mol Med (Berl). 2017. PMID: 27568040 Free PMC article.
Generation of metastatic melanoma specific antibodies by affinity purification.
Schütz B, Koppensteiner A, Schörghofer D, Kinslechner K, Timelthaler G, Eferl R, Hengstschläger M, Missbichler A, Hundsberger H, Mikula M. Schütz B, et al. Among authors: timelthaler g. Sci Rep. 2016 Nov 17;6:37253. doi: 10.1038/srep37253. Sci Rep. 2016. PMID: 27853253 Free PMC article.
EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
Srivatsa S, Paul MC, Cardone C, Holcmann M, Amberg N, Pathria P, Diamanti MA, Linder M, Timelthaler G, Dienes HP, Kenner L, Wrba F, Prager GW, Rose-John S, Eferl R, Liguori G, Botti G, Martinelli E, Greten FR, Ciardiello F, Sibilia M. Srivatsa S, et al. Among authors: timelthaler g. Gastroenterology. 2017 Jul;153(1):178-190.e10. doi: 10.1053/j.gastro.2017.03.053. Epub 2017 Apr 9. Gastroenterology. 2017. PMID: 28400195 Free PMC article.
39 results