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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. Schneider M, et al. Among authors: ting jp. Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5. Nat Immunol. 2012. PMID: 22863753 Free PMC article.
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Koblansky AA, Truax AD, Liu R, Montgomery SA, Ding S, Wilson JE, Brickey WJ, Mühlbauer M, McFadden RM, Hu P, Li Z, Jobin C, Lund PK, Ting JP. Koblansky AA, et al. Among authors: ting jp. Cell Rep. 2016 Mar 22;14(11):2562-75. doi: 10.1016/j.celrep.2016.02.064. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26971998 Free PMC article.
How Mouse Macrophages Sense What Is Going On.
Ley K, Pramod AB, Croft M, Ravichandran KS, Ting JP. Ley K, et al. Among authors: ting jp. Front Immunol. 2016 Jun 2;7:204. doi: 10.3389/fimmu.2016.00204. eCollection 2016. Front Immunol. 2016. PMID: 27313577 Free PMC article. Review.
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.
Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. Feng H, et al. Among authors: ting jp. Nat Immunol. 2017 Dec;18(12):1299-1309. doi: 10.1038/ni.3853. Epub 2017 Oct 2. Nat Immunol. 2017. PMID: 28967880 Free PMC article.
371 results