Tohnai G - Search Results

1

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy.

Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Noda S, Murakami A, Onodera K, Okada Y, Nakatochi M, Tsukagoshi Okabe Y, Shimizu S, Mizuno M, Adachi H, Okano H, Sobue G, Katsuno M. Iida M, et al. Among authors: tohnai g. Nat Commun. 2019 Sep 19;10(1):4262. doi: 10.1038/s41467-019-12282-7. Nat Commun. 2019. PMID: 31537808 Free PMC article.

2

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2.

Miyazaki Y, Adachi H, Katsuno M, Minamiyama M, Jiang YM, Huang Z, Doi H, Matsumoto S, Kondo N, Iida M, Tohnai G, Tanaka F, Muramatsu S, Sobue G. Miyazaki Y, et al. Among authors: tohnai g. Nat Med. 2012 Jul;18(7):1136-41. doi: 10.1038/nm.2791. Nat Med. 2012. PMID: 22660636

3

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration.

Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G. Kondo N, et al. Among authors: tohnai g. Nat Commun. 2013;4:1405. doi: 10.1038/ncomms2417. Nat Commun. 2013. PMID: 23360996 Free article.

4

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.

Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G. Qiang Q, et al. Among authors: tohnai g. J Neurochem. 2013 Jul;126(1):122-30. doi: 10.1111/jnc.12172. Epub 2013 Feb 27. J Neurochem. 2013. PMID: 23363377 Free article.

5

p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.

Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Qiang Q, Tanaka F, Yanagawa T, Warabi E, Ishii T, Sobue G. Doi H, et al. Among authors: tohnai g. J Neurosci. 2013 May 1;33(18):7710-27. doi: 10.1523/JNEUROSCI.3021-12.2013. J Neurosci. 2013. PMID: 23637164 Free PMC article.

6

Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy.

Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Nakatsuji H, Qiang Q, Ding Y, Watanabe H, Yamamoto M, Ohtsuka K, Sobue G. Tohnai G, et al. Hum Mol Genet. 2014 Jul 1;23(13):3552-65. doi: 10.1093/hmg/ddu066. Epub 2014 Feb 18. Hum Mol Genet. 2014. PMID: 24549037

7

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors.

Iida M, Katsuno M, Nakatsuji H, Adachi H, Kondo N, Miyazaki Y, Tohnai G, Ikenaka K, Watanabe H, Yamamoto M, Kishida K, Sobue G. Iida M, et al. Among authors: tohnai g. Hum Mol Genet. 2015 Jan 15;24(2):314-29. doi: 10.1093/hmg/ddu445. Epub 2014 Aug 28. Hum Mol Genet. 2015. PMID: 25168383

8

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy.

Sahashi K, Katsuno M, Hung G, Adachi H, Kondo N, Nakatsuji H, Tohnai G, Iida M, Bennett CF, Sobue G. Sahashi K, et al. Among authors: tohnai g. Hum Mol Genet. 2015 Nov 1;24(21):5985-94. doi: 10.1093/hmg/ddv300. Epub 2015 Jul 30. Hum Mol Genet. 2015. PMID: 26231218

9

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration.

Ding Y, Adachi H, Katsuno M, Huang Z, Jiang YM, Kondo N, Iida M, Tohnai G, Nakatsuji H, Funakoshi H, Nakamura T, Sobue G. Ding Y, et al. Among authors: tohnai g. Biochem Biophys Res Commun. 2015 Dec 25;468(4):677-83. doi: 10.1016/j.bbrc.2015.11.015. Epub 2015 Nov 7. Biochem Biophys Res Commun. 2015. PMID: 26551462

10

Next-generation sequencing of 28 ALS-related genes in a Japanese ALS cohort.

Nakamura R, Sone J, Atsuta N, Tohnai G, Watanabe H, Yokoi D, Nakatochi M, Watanabe H, Ito M, Senda J, Katsuno M, Tanaka F, Li Y, Izumi Y, Morita M, Taniguchi A, Kano O, Oda M, Kuwabara S, Abe K, Aiba I, Okamoto K, Mizoguchi K, Hasegawa K, Aoki M, Hattori N, Tsuji S, Nakashima K, Kaji R, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS). Nakamura R, et al. Among authors: tohnai g. Neurobiol Aging. 2016 Mar;39:219.e1-8. doi: 10.1016/j.neurobiolaging.2015.11.030. Epub 2015 Dec 7. Neurobiol Aging. 2016. PMID: 26742954

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