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A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing antibodies but does not influence pre-existing intestinal immunity.
Nochi T, Yuki Y, Katakai Y, Shibata H, Tokuhara D, Mejima M, Kurokawa S, Takahashi Y, Nakanishi U, Ono F, Mimuro H, Sasakawa C, Takaiwa F, Terao K, Kiyono H. Nochi T, et al. Among authors: tokuhara d. J Immunol. 2009 Nov 15;183(10):6538-44. doi: 10.4049/jimmunol.0901480. Epub 2009 Oct 30. J Immunol. 2009. PMID: 19880451
Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine.
Tokuhara D, Yuki Y, Nochi T, Kodama T, Mejima M, Kurokawa S, Takahashi Y, Nanno M, Nakanishi U, Takaiwa F, Honda T, Kiyono H. Tokuhara D, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8794-9. doi: 10.1073/pnas.0914121107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421480 Free PMC article.
Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.
Nochi T, Yuki Y, Takahashi H, Sawada S, Mejima M, Kohda T, Harada N, Kong IG, Sato A, Kataoka N, Tokuhara D, Kurokawa S, Takahashi Y, Tsukada H, Kozaki S, Akiyoshi K, Kiyono H. Nochi T, et al. Among authors: tokuhara d. Nat Mater. 2010 Jul;9(7):572-8. doi: 10.1038/nmat2784. Epub 2010 Jun 20. Nat Mater. 2010. PMID: 20562880
Novel vaccine development strategies for inducing mucosal immunity.
Fujkuyama Y, Tokuhara D, Kataoka K, Gilbert RS, McGhee JR, Yuki Y, Kiyono H, Fujihashi K. Fujkuyama Y, et al. Among authors: tokuhara d. Expert Rev Vaccines. 2012 Mar;11(3):367-79. doi: 10.1586/erv.11.196. Expert Rev Vaccines. 2012. PMID: 22380827 Free PMC article. Review.
Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.
Fukuyama Y, Tokuhara D, Sekine S, Aso K, Kataoka K, Davydova J, Yamamoto M, Gilbert RS, Tokuhara Y, Fujihashi K, Kunisawa J, Yuki Y, Kiyono H, McGhee JR, Fujihashi K. Fukuyama Y, et al. Among authors: tokuhara y, tokuhara d. PLoS One. 2013;8(4):e60453. doi: 10.1371/journal.pone.0060453. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565250 Free PMC article.
Induction of toxin-specific neutralizing immunity by molecularly uniform rice-based oral cholera toxin B subunit vaccine without plant-associated sugar modification.
Yuki Y, Mejima M, Kurokawa S, Hiroiwa T, Takahashi Y, Tokuhara D, Nochi T, Katakai Y, Kuroda M, Takeyama N, Kashima K, Abe M, Chen Y, Nakanishi U, Masumura T, Takeuchi Y, Kozuka-Hata H, Shibata H, Oyama M, Tanaka K, Kiyono H. Yuki Y, et al. Among authors: tokuhara d. Plant Biotechnol J. 2013 Sep;11(7):799-808. doi: 10.1111/pbi.12071. Epub 2013 Apr 22. Plant Biotechnol J. 2013. PMID: 23601492 Free article.
73 results