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Wide geographic distribution of a unique methicillin-resistant Staphylococcus aureus clone in Hungarian hospitals.
de Lencastre H, Severina EP, Milch H, Thege MK, Tomasz A. de Lencastre H, et al. Clin Microbiol Infect. 1997 Jun;3(3):289-296. doi: 10.1111/j.1469-0691.1997.tb00616.x. Clin Microbiol Infect. 1997. PMID: 11864123
METHODS: Molecular fingerprinting methods were used: hybridization with a mecA-specific DNA probe after ClaI restriction; hybridization with a probe for Tn554; and pulsed-field gel electrophoresis after Smal digestion of chromosomal DNA. ...Only one of the MRSA isol …
METHODS: Molecular fingerprinting methods were used: hybridization with a mecA-specific DNA probe after ClaI restriction; hybridizati …
Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A.
de Jonge BL, Chang YS, Gage D, Tomasz A. de Jonge BL, et al. J Biol Chem. 1992 Jun 5;267(16):11248-54. J Biol Chem. 1992. PMID: 1597460
This extra PBP is thought to be a transpeptidase essential for the continued cell wall synthesis and growth in the presence of beta-lactam antibiotics. ...Our experiments provided no experimental data for a unique transpeptidase activity associated with PBP2A....
This extra PBP is thought to be a transpeptidase essential for the continued cell wall synthesis and growth in the presence of beta-l …
Naturally occurring peptidoglycan variants of Streptococcus pneumoniae.
Severin A, Tomasz A. Severin A, et al. J Bacteriol. 1996 Jan;178(1):168-74. doi: 10.1128/jb.178.1.168-174.1996. J Bacteriol. 1996. PMID: 8550412 Free PMC article.
Analysis by high-performance liquid chromatography of the stem peptide composition of cell walls purified from a large number of pneumococcal strains indicates that these bacteria produce a highly conserved species-specific peptidoglycan independent of serotype, iso …
Analysis by high-performance liquid chromatography of the stem peptide composition of cell walls purified from a large number of pneu …
Selective lysis of cultures and cell walls of penicillin-resistant but not penicillin-susceptible Streptococcus pneumoniae strains by a murein hydrolase complex.
Severin A, Tomasz A. Severin A, et al. J Bacteriol. 1995 Jun;177(11):3316-9. doi: 10.1128/jb.177.11.3316-3319.1995. J Bacteriol. 1995. PMID: 7768833 Free PMC article.
A murein hydrolase complex selectively lysed cultures of penicillin-resistant pneumococci and their cell walls in which the majority of muropeptide subunits were indirectly cross-linked through oligopeptide substituents (alanyl-alanine or alanyl-serine) on the epsilon-amin
A murein hydrolase complex selectively lysed cultures of penicillin-resistant pneumococci and their cell walls in which the majority
Distribution of methicillin-resistant Staphylococcus aureus clones among health care facilities in Connecticut, New Jersey, and Pennsylvania.
Roberts RB, Chung M, de Lencastre H, Hargrave J, Tomasz A, Nicolau DP, John JF Jr, Korzeniowski O; Tri-State MRSA Collaborative Study Group. Roberts RB, et al. Microb Drug Resist. 2000 Fall;6(3):245-51. doi: 10.1089/mdr.2000.6.245. Microb Drug Resist. 2000. PMID: 11144425
A previous surveillance study conducted in 12 hospitals in New York City in 1996 identified a unique multidrug-resistant genetic lineage of methicillin-resistant Staphylococcus aureus (MRSA) that was widespread and accounted for as much as 42% of all the MRSA isolat
A previous surveillance study conducted in 12 hospitals in New York City in 1996 identified a unique multidrug-resistant genet
Geographic spread of epidemic multiresistant Staphylococcus aureus clone in Brazil.
Teixeira LA, Resende CA, Ormonde LR, Rosenbaum R, Figueiredo AM, de Lencastre H, Tomasz A. Teixeira LA, et al. J Clin Microbiol. 1995 Sep;33(9):2400-4. doi: 10.1128/JCM.33.9.2400-2404.1995. J Clin Microbiol. 1995. PMID: 7494036 Free PMC article.
Eighty-five of the 152 isolates were identified as methicillin-resistant S. aureus (MRSA) by using a combination of an agar dilution screen and a mecA gene-specific DNA probe. ...The overwhelming majority of the isolates shared a common pulsed-field gel elect …
Eighty-five of the 152 isolates were identified as methicillin-resistant S. aureus (MRSA) by using a combination of an agar dilution …
Evidence for the geographic spread of a methicillin-resistant Staphylococcus aureus clone between Portugal and Spain.
Sanches IS, Ramirez M, Troni H, Abecassis M, Padua M, Tomasz A, de Lencastre H. Sanches IS, et al. J Clin Microbiol. 1995 May;33(5):1243-6. doi: 10.1128/JCM.33.5.1243-1246.1995. J Clin Microbiol. 1995. PMID: 7615735 Free PMC article.
Methicillin-resistant Staphylococcus aureus (MRSA) isolates collected during a 7-month period in 1992 and 1993 at Hospital Pulido Valente (340 beds), Lisbon, Portugal, were characterized by a combination of genotypic and phenotypic methods. ...Most of these (37 of 3 …
Methicillin-resistant Staphylococcus aureus (MRSA) isolates collected during a 7-month period in 1992 and 1993 at Hospital Pulido Val …
Genetic organization of the mecA region in methicillin-susceptible and methicillin-resistant strains of Staphylococcus sciuri.
Wu S, de Lencastre H, Tomasz A. Wu S, et al. J Bacteriol. 1998 Jan;180(2):236-42. doi: 10.1128/JB.180.2.236-242.1998. J Bacteriol. 1998. PMID: 9440511 Free PMC article.
A homolog of the Staphylococcus aureus methicillin resistance gene mecA was recently shown to be ubiquitous in independent isolates of the animal species Staphylococcus sciuri. The mecA gene homolog and regions flanking it were cloned and sequenced from four strains of S.
A homolog of the Staphylococcus aureus methicillin resistance gene mecA was recently shown to be ubiquitous in independent isolates o
Transcriptional analysis of the Staphylococcus aureus penicillin binding protein 2 gene.
Pinho MG, de Lencastre H, Tomasz A. Pinho MG, et al. J Bacteriol. 1998 Dec;180(23):6077-81. J Bacteriol. 1998. PMID: 9829914 Free PMC article.
Sequencing of the vicinity of the staphylococcal pbp2 gene and transcriptional analysis by primer extension and promoter fusions were used to show that pbp2 is part of an operon that also includes a gene with high homology to prfA of Bacillus subtilis. ...It was recently r …
Sequencing of the vicinity of the staphylococcal pbp2 gene and transcriptional analysis by primer extension and promoter fusions were used t …
Spread and maintenance of a dominant methicillin-resistant Staphylococcus aureus (MRSA) clone during an outbreak of MRSA disease in a Spanish hospital.
Dominguez MA, de Lencastre H, Linares J, Tomasz A. Dominguez MA, et al. J Clin Microbiol. 1994 Sep;32(9):2081-7. doi: 10.1128/JCM.32.9.2081-2087.1994. J Clin Microbiol. 1994. PMID: 7814528 Free PMC article.
A single MRSA clone (I::B::a) belonging to ClaI type I, pulsed-field gel electrophoretic pattern B, and Tn554 pattern a was responsible for the great majority of infections (73% of blood cultures and 79% of specimens from other clinical sources). ...
A single MRSA clone (I::B::a) belonging to ClaI type I, pulsed-field gel electrophoretic pattern B, and Tn554 pattern a
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