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Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5.
Yamamura T, Horinouchi T, Adachi T, Terakawa M, Takaoka Y, Omachi K, Takasato M, Takaishi K, Shoji T, Onishi Y, Kanazawa Y, Koizumi M, Tomono Y, Sugano A, Shono A, Minamikawa S, Nagano C, Sakakibara N, Ishiko S, Aoto Y, Kamura M, Harita Y, Miura K, Kanda S, Morisada N, Rossanti R, Ye MJ, Nozu Y, Matsuo M, Kai H, Iijima K, Nozu K. Yamamura T, et al. Among authors: tomono y. Nat Commun. 2020 Jun 2;11(1):2777. doi: 10.1038/s41467-020-16605-x. Nat Commun. 2020. PMID: 32488001 Free PMC article.
Lack of collagen α6(IV) chain in mice does not cause severe-to-profound hearing loss or cochlear malformation, a distinct phenotype from nonsyndromic hearing loss with COL4A6 missense mutation.
Tang S, Yonezawa T, Maeda Y, Ono M, Maeba T, Miyoshi T, Momota R, Tomono Y, Oohashi T. Tang S, et al. Among authors: tomono y. PLoS One. 2021 Apr 13;16(4):e0249909. doi: 10.1371/journal.pone.0249909. eCollection 2021. PLoS One. 2021. PMID: 33848312 Free PMC article.
Oxidative stress balance is dysregulated and represents an additional target for treating cholangiocarcinoma.
Uchida D, Takaki A, Ishikawa H, Tomono Y, Kato H, Tsutsumi K, Tamaki N, Maruyama T, Tomofuji T, Tsuzaki R, Yasunaka T, Koike K, Matsushita H, Ikeda F, Miyake Y, Shiraha H, Nouso K, Yoshida R, Umeda Y, Shinoura S, Yagi T, Fujiwara T, Morita M, Fukushima M, Yamamoto K, Okada H. Uchida D, et al. Among authors: tomono y. Free Radic Res. 2016 Jul;50(7):732-43. doi: 10.3109/10715762.2016.1172071. Epub 2016 Apr 25. Free Radic Res. 2016. PMID: 27021847
Iron depletion enhances the effect of sorafenib in hepatocarcinoma.
Urano S, Ohara T, Noma K, Katsube R, Ninomiya T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Nouso K, Matsukawa A, Yamamoto K, Fujiwara T. Urano S, et al. Among authors: tomono y. Cancer Biol Ther. 2016 Jun 2;17(6):648-56. doi: 10.1080/15384047.2016.1177677. Epub 2016 Apr 18. Cancer Biol Ther. 2016. PMID: 27089255 Free PMC article.
Biallelic COLGALT1 variants are associated with cerebral small vessel disease.
Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N. Miyatake S, et al. Among authors: tomono y. Ann Neurol. 2018 Dec;84(6):843-853. doi: 10.1002/ana.25367. Epub 2018 Nov 30. Ann Neurol. 2018. PMID: 30412317
Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.
Makihara H, Inaba H, Enomoto A, Tanaka H, Tomono Y, Ushida K, Goto M, Kurita K, Nishida Y, Kasahara K, Goto H, Inagaki M. Makihara H, et al. Among authors: tomono y. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1323-9. doi: 10.1016/j.bbrc.2016.08.122. Epub 2016 Aug 23. Biochem Biophys Res Commun. 2016. PMID: 27565725 Free article.
170 results