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Showing results for tonic bales
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Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice.
Hunter JM, Cirrito JR, Restivo JL, Kinley RD, Sullivan PM, Holtzman DM, Koger D, Delong C, Lin S, Zhao L, Liu F, Bales K, Paul SM. Hunter JM, et al. Brain Res. 2012 Jul 27;1467:120-32. doi: 10.1016/j.brainres.2012.05.048. Epub 2012 Jun 5. Brain Res. 2012. PMID: 22682924
We now report the emergence of a seizure phenotype in aged apolipoprotein E4 (apoE4) targeted replacement (TR) mice but not in age-matched apoE2 TR or apoE3 TR mice. Tonic-clonic seizures developed spontaneously after 5 months of age in apoE4 TR mice and are triggered by m …
We now report the emergence of a seizure phenotype in aged apolipoprotein E4 (apoE4) targeted replacement (TR) mice but not in age-matched a …