Tort JF - Search Results

1

Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.

Corvo I, O'Donoghue AJ, Pastro L, Pi-Denis N, Eroy-Reveles A, Roche L, McKerrow JH, Dalton JP, Craik CS, Caffrey CR, Tort JF. Corvo I, et al. Among authors: tort jf. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2269. doi: 10.1371/journal.pntd.0002269. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875031 Free PMC article.

2

The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen.

Corvo I, Cancela M, Cappetta M, Pi-Denis N, Tort JF, Roche L. Corvo I, et al. Among authors: tort jf. Mol Biochem Parasitol. 2009 Sep;167(1):41-7. doi: 10.1016/j.molbiopara.2009.04.005. Epub 2009 Apr 19. Mol Biochem Parasitol. 2009. PMID: 19383516

3

Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

Robinson MW, Corvo I, Jones PM, George AM, Padula MP, To J, Cancela M, Rinaldi G, Tort JF, Roche L, Dalton JP. Robinson MW, et al. Among authors: tort jf. PLoS Negl Trop Dis. 2011 Apr 5;5(4):e1012. doi: 10.1371/journal.pntd.0001012. PLoS Negl Trop Dis. 2011. PMID: 21483711 Free PMC article.

4

Identification of Chalcones as Fasciola hepatica Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational Approach.

Ferraro F, Merlino A, Dell Oca N, Gil J, Tort JF, Gonzalez M, Cerecetto H, Cabrera M, Corvo I. Ferraro F, et al. Among authors: tort jf. PLoS Negl Trop Dis. 2016 Jul 27;10(7):e0004834. doi: 10.1371/journal.pntd.0004834. eCollection 2016 Jul. PLoS Negl Trop Dis. 2016. PMID: 27463369 Free PMC article.

5

Cathepsin L3 From Fasciola hepatica Induces NLRP3 Inflammasome Alternative Activation in Murine Dendritic Cells.

Celias DP, Corvo I, Silvane L, Tort JF, Chiapello LS, Fresno M, Arranz A, Motrán CC, Cervi L. Celias DP, et al. Among authors: tort jf. Front Immunol. 2019 Mar 22;10:552. doi: 10.3389/fimmu.2019.00552. eCollection 2019. Front Immunol. 2019. PMID: 30967874 Free PMC article.

6

A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica.

Cancela M, Acosta D, Rinaldi G, Silva E, Durán R, Roche L, Zaha A, Carmona C, Tort JF. Cancela M, et al. Among authors: tort jf. Biochimie. 2008 Oct;90(10):1461-75. doi: 10.1016/j.biochi.2008.04.020. Epub 2008 Jun 5. Biochimie. 2008. PMID: 18573308

7

Substrate Specificity of Cysteine Proteases Beyond the S₂ Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L.

Corvo I, Ferraro F, Merlino A, Zuberbühler K, O'Donoghue AJ, Pastro L, Pi-Denis N, Basika T, Roche L, McKerrow JH, Craik CS, Caffrey CR, Tort JF. Corvo I, et al. Among authors: tort jf. Front Mol Biosci. 2018 Apr 19;5:40. doi: 10.3389/fmolb.2018.00040. eCollection 2018. Front Mol Biosci. 2018. PMID: 29725596 Free PMC article.

8

Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.

Stack CM, Caffrey CR, Donnelly SM, Seshaadri A, Lowther J, Tort JF, Collins PR, Robinson MW, Xu W, McKerrow JH, Craik CS, Geiger SR, Marion R, Brinen LS, Dalton JP. Stack CM, et al. Among authors: tort jf. J Biol Chem. 2008 Apr 11;283(15):9896-908. doi: 10.1074/jbc.M708521200. Epub 2007 Dec 26. J Biol Chem. 2008. PMID: 18160404 Free PMC article.

9

Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain.

Cappetta M, Roth I, Díaz A, Tort J, Roche L. Cappetta M, et al. Biol Chem. 2002 Jul-Aug;383(7-8):1215-21. doi: 10.1515/BC.2002.134. Biol Chem. 2002. PMID: 12437108

10

RNA interference in Fasciola hepatica newly excysted juveniles: long dsRNA induces more persistent silencing than siRNA.

Dell'Oca N, Basika T, Corvo I, Castillo E, Brindley PJ, Rinaldi G, Tort JF. Dell'Oca N, et al. Among authors: tort jf. Mol Biochem Parasitol. 2014 Oct;197(1-2):28-35. doi: 10.1016/j.molbiopara.2014.10.001. Epub 2014 Oct 12. Mol Biochem Parasitol. 2014. PMID: 25307443

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