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O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis.
Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya MA, Wang X, Simons BW, Ballew M, Nugent K, Groves J, Williams RD, Shiraishi T, Verdone J, Yildirir G, Henry R, Zhang B, Wong J, Wang KK, Nelkin BD, Pienta KJ, Felsher D, Zachara NE, Tran PT. Taparra K, et al. Among authors: tran pt. J Clin Invest. 2018 Nov 1;128(11):4924-4937. doi: 10.1172/JCI94844. Epub 2018 Sep 24. J Clin Invest. 2018. PMID: 30130254 Free PMC article.
Hypoxia in models of lung cancer: implications for targeted therapeutics.
Graves EE, Vilalta M, Cecic IK, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ. Graves EE, et al. Among authors: tran pt. Clin Cancer Res. 2010 Oct 1;16(19):4843-52. doi: 10.1158/1078-0432.CCR-10-1206. Epub 2010 Sep 21. Clin Cancer Res. 2010. PMID: 20858837 Free PMC article.
Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.
Tran PT, Shroff EH, Burns TF, Thiyagarajan S, Das ST, Zabuawala T, Chen J, Cho YJ, Luong R, Tamayo P, Salih T, Aziz K, Adam SJ, Vicent S, Nielsen CH, Withofs N, Sweet-Cordero A, Gambhir SS, Rudin CM, Felsher DW. Tran PT, et al. PLoS Genet. 2012;8(5):e1002650. doi: 10.1371/journal.pgen.1002650. Epub 2012 May 24. PLoS Genet. 2012. PMID: 22654667 Free PMC article.
Hedgehog pathway inhibition radiosensitizes non-small cell lung cancers.
Zeng J, Aziz K, Chettiar ST, Aftab BT, Armour M, Gajula R, Gandhi N, Salih T, Herman JM, Wong J, Rudin CM, Tran PT, Hales RK. Zeng J, et al. Among authors: tran pt. Int J Radiat Oncol Biol Phys. 2013 May 1;86(1):143-9. doi: 10.1016/j.ijrobp.2012.10.014. Epub 2012 Nov 20. Int J Radiat Oncol Biol Phys. 2013. PMID: 23182391 Free PMC article.
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Gandhi N, Wild AT, Chettiar ST, Aziz K, Kato Y, Gajula RP, Williams RD, Cades JA, Annadanam A, Song D, Zhang Y, Hales RK, Herman JM, Armour E, DeWeese TL, Schaeffer EM, Tran PT. Gandhi N, et al. Among authors: tran pt. Cancer Biol Ther. 2013 Apr;14(4):347-56. doi: 10.4161/cbt.23626. Epub 2013 Jan 28. Cancer Biol Ther. 2013. PMID: 23358469 Free PMC article.
438 results