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Tranexamic Acid reduces perioperative blood loss in adult patients having spinal fusion surgery.
Wong J, El Beheiry H, Rampersaud YR, Lewis S, Ahn H, De Silva Y, Abrishami A, Baig N, McBroom RJ, Chung F. Wong J, et al. Anesth Analg. 2008 Nov;107(5):1479-86. doi: 10.1213/ane.0b013e3181831e44. Anesth Analg. 2008. PMID: 18931202 Clinical Trial.
The objective of this randomized, prospective, double-blind, multicenter study was to evaluate the efficacy of tranexamic acid (TXA) in reducing perioperative blood loss and transfusion in adult patients having elective post …
The objective of this randomized, prospective, double-blind, multicenter study was to evaluate the efficacy of tranexamic acid …
Efficacy of Tranexamic Acid on Blood Loss in Thoracolumbar Spinal Fusion Surgery.
Emrah K, Ali AH, Utku O, Murat K, Kenan S, Deniz B. Emrah K, et al. J Coll Physicians Surg Pak. 2021 Dec;31(12):1449-1454. doi: 10.29271/jcpsp.2021.12.1449. J Coll Physicians Surg Pak. 2021. PMID: 34794286
Systemic side effects, especially thromboembolism, were not observed in any of the patients. CONCLUSION: The topical use of TXA in spinal fusion surgery reduced perioperative blood loss. Key Words: Blood loss, …
Systemic side effects, especially thromboembolism, were not observed in any of the patients. CONCLUSION: The topical use of TXA in …
Tranexamic Acid in Thoracic and Lumbar Fusions and Perioperative Blood Loss.
Wanderman N, Robinson W, Carlson B, Bydon M, Currier B, Huddleston P, Nassr A, Freedman B. Wanderman N, et al. Clin Spine Surg. 2019 Dec;32(10):E462-E468. doi: 10.1097/BSD.0000000000000851. Clin Spine Surg. 2019. PMID: 31169616
OBJECTIVE: The objective of this study was to examine the impact of tranexamic acid (TXA) on total perioperative wound output following thoracic and lumbar spinal fusions. ...However, with surgeries involving fusions >5 levels, TXA may increa …
OBJECTIVE: The objective of this study was to examine the impact of tranexamic acid (TXA) on total perioperative wound …
Tranexamic acid reduce hidden blood loss in posterior lumbar interbody fusion (PLIF) surgery.
Xu D, Chen X, Li Z, Ren Z, Zhuang Q, Li S. Xu D, et al. Medicine (Baltimore). 2020 Mar;99(11):e19552. doi: 10.1097/MD.0000000000019552. Medicine (Baltimore). 2020. PMID: 32176112 Free PMC article. Clinical Trial.
BACKGROUND: Posterior lumbar interbody fusion (PLIF) surgery is associated with significant blood loss; however, few studies have focused on hidden blood loss (HBL) in PLIF or its regulatory factors. The purpose of this study was to explo …
BACKGROUND: Posterior lumbar interbody fusion (PLIF) surgery is associated with significant blood loss; however, …
The Perioperative Efficacy and Safety of Antifibrinolytics in Adult Spinal Fusion Surgery: A Systematic Review and Meta-analysis.
Lu VM, Ho YT, Nambiar M, Mobbs RJ, Phan K. Lu VM, et al. Spine (Phila Pa 1976). 2018 Aug;43(16):E949-E958. doi: 10.1097/BRS.0000000000002580. Spine (Phila Pa 1976). 2018. PMID: 30063223 Review.
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Compare outcomes of adult patients undergoing spinal fusion surgery who receive and do not receive perioperative antifibrinolytics to reduce operative blood …
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Compare outcomes of adult patients undergoing spinal f …
Randomized, controlled trial of two tranexamic acid dosing protocols in adult spinal deformity surgery.
Clohisy JCF, Lenke LG, Dafrawy MHE, Wolfe RC, Frazier E, Kelly MP. Clohisy JCF, et al. Spine Deform. 2022 Nov;10(6):1399-1406. doi: 10.1007/s43390-022-00539-z. Epub 2022 Jun 25. Spine Deform. 2022. PMID: 35751772 Clinical Trial.
BACKGROUND: Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic surgery. ...Intraoperative estimated blood loss (EBL) was calculated by suction canisters minus irrigation plus estimat …
BACKGROUND: Tranexamic acid (TXA) is an anti-fibrinolytic effective in reducing blood loss in orthopedic …
Antifibrinolytics reduce blood loss in adult spinal deformity surgery: a prospective, randomized controlled trial.
Peters A, Verma K, Slobodyanyuk K, Cheriyan T, Hoelscher C, Schwab F, Lonner B, Huncke T, Lafage V, Errico T. Peters A, et al. Spine (Phila Pa 1976). 2015 Apr 15;40(8):E443-9. doi: 10.1097/BRS.0000000000000799. Spine (Phila Pa 1976). 2015. PMID: 25868100 Clinical Trial.
OBJECTIVE: The purpose of this study was to provide high-quality evidence regarding the comparative efficacies of TXA, EACA, and placebo in reducing blood loss and transfusion requirements in patients undergoing posterior spinal fusion …
OBJECTIVE: The purpose of this study was to provide high-quality evidence regarding the comparative efficacies of TXA, EACA, and placebo in …
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis: A randomized trial.
Shi H, Ou Y, Jiang D, Quan Z, Zhao Z, Zhu Y. Shi H, et al. Medicine (Baltimore). 2017 Jan;96(1):e5718. doi: 10.1097/MD.0000000000005718. Medicine (Baltimore). 2017. PMID: 28072709 Free PMC article. Clinical Trial.
This study aimed to evaluate the effect and safety of TA in reducing perioperative blood loss in posterior lumbar surgery for stenosis or spondylolisthesis. ...CONCLUSION: TA significantly reduced the perioperative blood …
This study aimed to evaluate the effect and safety of TA in reducing perioperative blood loss in posterior lumba …
Patient Blood Management During Lumbar Spinal Fusion Surgery.
Kang T, Park SY, Nam JJ, Lee SH, Park JH, Suh SW. Kang T, et al. World Neurosurg. 2019 Oct;130:e566-e572. doi: 10.1016/j.wneu.2019.06.153. Epub 2019 Jun 26. World Neurosurg. 2019. PMID: 31254701
We performed the present study to examine the effects of PBM in spinal fusion surgery. METHODS: A total of 154 patients who had undergone 1- and 2-level posterior lumbar interbody fusion for degenerative lumbar disease were included. ...CONCLUSI …
We performed the present study to examine the effects of PBM in spinal fusion surgery. METHODS: A total of 154 patie …
Oral Is as Effective as Intravenous Tranexamic Acid at Reducing Blood Loss in Thoracolumbar Spinal Fusions: A Prospective Randomized Trial.
Yu CC, Fidai M, Washington T, Bartol S, Graziano G. Yu CC, et al. Spine (Phila Pa 1976). 2022 Jan 15;47(2):91-98. doi: 10.1097/BRS.0000000000004157. Spine (Phila Pa 1976). 2022. PMID: 34224510 Clinical Trial.
SUMMARY OF BACKGROUND DATA: The use of antifibrinolytic agents such as tranexamic acid (TXA) to decrease operative blood loss and allogenic blood transfusions is well documented in the literature. ...CONCLUSION: Patients treated wi …
SUMMARY OF BACKGROUND DATA: The use of antifibrinolytic agents such as tranexamic acid (TXA) to decrease operative b …
37 results