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Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4.
Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Bachtell R, et al. CNS Neurol Disord Drug Targets. 2015;14(6):692-9. doi: 10.2174/1871527314666150529132503. CNS Neurol Disord Drug Targets. 2015. PMID: 26022268 Free PMC article. Review.
Indeed, selective pharmacological blockade of TLR4 activation, such as with the non-opioid TLR4 antagonist (+)-naltrexone, suppresses a number of indices of drug reward/reinforcement. ...Genetic disruption of TLR4 signaling recapitulates the eff …
Indeed, selective pharmacological blockade of TLR4 activation, such as with the non-opioid TLR4 antagonist (+)-naltr