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Urinary phenotyping of SARS-CoV-2 infection connects clinical diagnostics with metabolomics and uncovers impaired NAD+ pathway and SIRT1 activation.
Lonati C, Berezhnoy G, Lawler N, Masuda R, Kulkarni A, Sala S, Nitschke P, Zizmare L, Bucci D, Cannet C, Schäfer H, Singh Y, Gray N, Lodge S, Nicholson J, Merle U, Wist J, Trautwein C. Lonati C, et al. Among authors: trautwein c. Clin Chem Lab Med. 2023 Nov 14;62(4):770-788. doi: 10.1515/cclm-2023-1017. Print 2024 Mar 25. Clin Chem Lab Med. 2023. PMID: 37955280 Free article.
DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs).
Singh Y, Trautwein C, Dhariwal A, Salker MS, Alauddin M, Zizmare L, Pelzl L, Feger M, Admard J, Casadei N, Föller M, Pachauri V, Park DS, Mak TW, Frick JS, Wallwiener D, Brucker SY, Lang F, Riess O. Singh Y, et al. Among authors: trautwein c. Sci Rep. 2020 Sep 30;10(1):16131. doi: 10.1038/s41598-020-72903-w. Sci Rep. 2020. PMID: 32999308 Free PMC article.
Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors.
Bus C, Zizmare L, Feldkaemper M, Geisler S, Zarani M, Schaedler A, Klose F, Admard J, Mageean CJ, Arena G, Fallier-Becker P, Ugun-Klusek A, Maruszczak KK, Kapolou K, Schmid B, Rapaport D, Ueffing M, Casadei N, Krüger R, Gasser T, Vogt Weisenhorn DM, Kahle PJ, Trautwein C, Gloeckner CJ, Fitzgerald JC. Bus C, et al. Among authors: trautwein c. iScience. 2020 Nov 13;23(12):101797. doi: 10.1016/j.isci.2020.101797. eCollection 2020 Dec 18. iScience. 2020. PMID: 33299968 Free PMC article.
Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions.
Mehling R, Schwenck J, Lemberg C, Trautwein C, Zizmare L, Kramer D, Müller A, Fehrenbacher B, Gonzalez-Menendez I, Quintanilla-Martinez L, Schröder K, Brandes RP, Schaller M, Ruf W, Eichner M, Ghoreschi K, Röcken M, Pichler BJ, Kneilling M. Mehling R, et al. Among authors: trautwein c. Theranostics. 2021 Jan 1;11(2):470-490. doi: 10.7150/thno.51462. eCollection 2021. Theranostics. 2021. PMID: 33391487 Free PMC article.
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, Ossowski S, Salker MS, Casadei N, Riess O; Deutsche COVID-19 OMICS Initiate (DeCOI). Singh Y, et al. Among authors: trautwein c. Heliyon. 2021 Jun;7(6):e07147. doi: 10.1016/j.heliyon.2021.e07147. Epub 2021 May 28. Heliyon. 2021. PMID: 34075347 Free PMC article.
Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR-based urinary metabolomics.
Laugwitz L, Zizmare L, Santhanakumaran V, Cannet C, Böhringer J, Okun JG, Spraul M, Krägeloh-Mann I, Groeschel S, Trautwein C. Laugwitz L, et al. Among authors: trautwein c. JIMD Rep. 2022 Jan 27;63(2):168-180. doi: 10.1002/jmd2.12273. eCollection 2022 Mar. JIMD Rep. 2022. PMID: 35281658 Free PMC article.
842 results