Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2010 3
2011 4
2012 1
2013 3
2014 3
2015 5
2016 9
2017 7
2018 14
2019 15
2020 18
2021 21
2022 25
2023 24
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

144 results

Results by year

Filters applied: . Clear all
Page 1
Microglia states and nomenclature: A field at its crossroads.
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Paolicelli RC, et al. Among authors: tremblay me. Neuron. 2022 Nov 2;110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020. Neuron. 2022. PMID: 36327895 Free PMC article. Review.
Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." This dualistic classification of good or bad microglia is inconsistent with the wide repertoir …
Microglial research has advanced considerably in recent decades yet has been constrained by a rolling series of dichotomies such as "resting …
Morphology of Microglia Across Contexts of Health and Disease.
Savage JC, Carrier M, Tremblay MÈ. Savage JC, et al. Among authors: tremblay me. Methods Mol Biol. 2019;2034:13-26. doi: 10.1007/978-1-4939-9658-2_2. Methods Mol Biol. 2019. PMID: 31392674 Review.
Microglia, the brain's resident macrophages, are incredibly plastic and dynamic cells. ...Older animals occasionally contain dystrophic, senescent, and gitter cell-like microglia, and brain injury can be accompanied by an increase in rod cells. ...
Microglia, the brain's resident macrophages, are incredibly plastic and dynamic cells. ...Older animals occasionally contain dystroph …
ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.
Stratoulias V, Ruiz R, Kanatani S, Osman AM, Keane L, Armengol JA, Rodríguez-Moreno A, Murgoci AN, García-Domínguez I, Alonso-Bellido I, González Ibáñez F, Picard K, Vázquez-Cabrera G, Posada-Pérez M, Vernoux N, Tejera D, Grabert K, Cheray M, González-Rodríguez P, Pérez-Villegas EM, Martínez-Gallego I, Lastra-Romero A, Brodin D, Avila-Cariño J, Cao Y, Airavaara M, Uhlén P, Heneka MT, Tremblay MÈ, Blomgren K, Venero JL, Joseph B. Stratoulias V, et al. Among authors: tremblay me. Nat Neurosci. 2023 Jun;26(6):1008-1020. doi: 10.1038/s41593-023-01326-3. Epub 2023 May 11. Nat Neurosci. 2023. PMID: 37169859 Free PMC article.
ARG1(+) microglia are enriched in phagocytic inclusions and exhibit a distinct molecular signature, including upregulation of genes such as Apoe, Clec7a, Igf1, Lgals3 and Mgl2, compared to ARG1(-) microglia. Microglial-specific knockdown of Arg1 results in deficient …
ARG1(+) microglia are enriched in phagocytic inclusions and exhibit a distinct molecular signature, including upregulation of genes s …
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Bellver-Landete V, Bretheau F, Mailhot B, Vallières N, Lessard M, Janelle ME, Vernoux N, Tremblay MÈ, Fuehrmann T, Shoichet MS, Lacroix S. Bellver-Landete V, et al. Among authors: tremblay me. Nat Commun. 2019 Jan 31;10(1):518. doi: 10.1038/s41467-019-08446-0. Nat Commun. 2019. PMID: 30705270 Free PMC article.
Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI. We find that microglia are highly dynamic and proliferate extensively during the first two weeks, accumulating around the lesion. There, activated …
Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI. We find that …
Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice.
Bisht K, Okojie KA, Sharma K, Lentferink DH, Sun YY, Chen HR, Uweru JO, Amancherla S, Calcuttawala Z, Campos-Salazar AB, Corliss B, Jabbour L, Benderoth J, Friestad B, Mills WA 3rd, Isakson BE, Tremblay MÈ, Kuan CY, Eyo UB. Bisht K, et al. Among authors: tremblay me. Nat Commun. 2021 Sep 6;12(1):5289. doi: 10.1038/s41467-021-25590-8. Nat Commun. 2021. PMID: 34489419 Free PMC article.
Microglia are brain-resident immune cells with a repertoire of functions in the brain. ...Then, we give a detailed spatio-temporal characterization of these capillary-associated microglia (CAMs) comparing them with parenchymal microglia (PCMs) in their morpho …
Microglia are brain-resident immune cells with a repertoire of functions in the brain. ...Then, we give a detailed spatio-temporal ch …
Immunofluorescence Staining Using IBA1 and TMEM119 for Microglial Density, Morphology and Peripheral Myeloid Cell Infiltration Analysis in Mouse Brain.
González Ibanez F, Picard K, Bordeleau M, Sharma K, Bisht K, Tremblay MÈ. González Ibanez F, et al. Among authors: tremblay me. J Vis Exp. 2019 Oct 27;(152). doi: 10.3791/60510. J Vis Exp. 2019. PMID: 31710033
This is a protocol for the dual visualization of microglia and infiltrating macrophages in mouse brain tissue. TMEM119 (which labels microglia selectively), when combined with IBA1 (which provides an exceptional visualization of their morphology), allows investigati …
This is a protocol for the dual visualization of microglia and infiltrating macrophages in mouse brain tissue. TMEM119 (which labels …
Glutamate-induced excitotoxicity in Parkinson's disease: The role of glial cells.
Iovino L, Tremblay ME, Civiero L. Iovino L, et al. Among authors: tremblay me. J Pharmacol Sci. 2020 Nov;144(3):151-164. doi: 10.1016/j.jphs.2020.07.011. Epub 2020 Aug 1. J Pharmacol Sci. 2020. PMID: 32807662 Free article. Review.
Glutamate-induced excitotoxicity is mainly linked to an impaired ability of glial cells to reuptake and respond to glutamate, then this is considered a common hallmark in many neurodegenerative diseases, including Parkinson's disease (PD). In this review, we discuss the function …
Glutamate-induced excitotoxicity is mainly linked to an impaired ability of glial cells to reuptake and respond to glutamate, then this is c …
Plasticity of microglia.
Augusto-Oliveira M, Arrifano GP, Delage CI, Tremblay MÈ, Crespo-Lopez ME, Verkhratsky A. Augusto-Oliveira M, et al. Among authors: tremblay me. Biol Rev Camb Philos Soc. 2022 Feb;97(1):217-250. doi: 10.1111/brv.12797. Epub 2021 Sep 21. Biol Rev Camb Philos Soc. 2022. PMID: 34549510
The nervous tissue environment instigates the phenotypic metamorphosis of foetal macrophages into idiosyncratic surveilling microglia, which are generally characterised by a small cell body and highly ramified motile processes that constantly scan the nervous tissue for si …
The nervous tissue environment instigates the phenotypic metamorphosis of foetal macrophages into idiosyncratic surveilling microglia …
Physiology of Microglia.
Tay TL, Carrier M, Tremblay MÈ. Tay TL, et al. Among authors: tremblay me. Adv Exp Med Biol. 2019;1175:129-148. doi: 10.1007/978-981-13-9913-8_6. Adv Exp Med Biol. 2019. PMID: 31583587 Review.
Microglia constitute the major immune cells that permanently reside in the central nervous system (CNS) alongside neurons and other glial cells. ...Here, we highlight studies that demonstrate the embryonic yolk sac origin of microglia and describe factors, including …
Microglia constitute the major immune cells that permanently reside in the central nervous system (CNS) alongside neurons and other g …
Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice.
Picard K, Bisht K, Poggini S, Garofalo S, Golia MT, Basilico B, Abdallah F, Ciano Albanese N, Amrein I, Vernoux N, Sharma K, Hui CW, C Savage J, Limatola C, Ragozzino D, Maggi L, Branchi I, Tremblay MÈ. Picard K, et al. Among authors: tremblay me. Brain Behav Immun. 2021 Oct;97:423-439. doi: 10.1016/j.bbi.2021.07.022. Epub 2021 Jul 31. Brain Behav Immun. 2021. PMID: 34343616 Free article.
We first confirmed that microglia were depleted in GR in our model in males and females among the cingulate cortex and the hippocampus, both stress-sensitive brain regions. ...On the contrary, in CUMS condition, GR depleted-microglia showed reduced expression levels …
We first confirmed that microglia were depleted in GR in our model in males and females among the cingulate cortex and the hippocampu …
144 results