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6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.
J Med Chem. 2002 Sep 12;45(19):4171-87. doi: 10.1021/jm0208121.
J Med Chem. 2002.
PMID: 12213059
Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines.
Sauerberg P, Olesen PH, Nielsen S, Treppendahl S, Sheardown MJ, Honoré T, Mitch CH, Ward JS, Pike AJ, Bymaster FP, et al.
Sauerberg P, et al.
J Med Chem. 1992 Jun 12;35(12):2274-83. doi: 10.1021/jm00090a019.
J Med Chem. 1992.
PMID: 1613751
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3,4-O-diacetylisoproterenol. Preparation, structure proof, and beta-receptor effect.
Jakobsen P, Treppendahl S, Andersen PH, Klysner R, Geisler A, Teuber L.
Jakobsen P, et al.
J Med Chem. 1985 Dec;28(12):1962-4. doi: 10.1021/jm00150a036.
J Med Chem. 1985.
PMID: 2999409
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Synthesis and structural determination of stereoisomers of muscarinic ligands of the (3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicycloalkane type.
Olesen PH, Sauerberg P, Petersen TG, Treppendahl S, Bentzen B, Deeter J, Ward JS, Mitch CH, Lehmann SV.
Olesen PH, et al.
Chirality. 1997;9(8):739-49. doi: 10.1002/(SICI)1520-636X(1997)9:8<739::AID-CHIR5>3.0.CO;2-0.
Chirality. 1997.
PMID: 9435099
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(S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice.
Thomsen C, Klitgaard H, Sheardown M, Jackson HC, Eskesen K, Jacobsen P, Treppendahl S, Suzdak PD.
Thomsen C, et al.
J Neurochem. 1994 Jun;62(6):2492-5. doi: 10.1046/j.1471-4159.1994.62062492.x.
J Neurochem. 1994.
PMID: 8189254
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Spectrophotometric characteristics and assay of pure pyronin Y.
Jakobsen P, Lyon H, Treppendahl S.
Jakobsen P, et al.
Histochemistry. 1984;81(1):99-101. doi: 10.1007/BF00495408.
Histochemistry. 1984.
PMID: 6469724
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