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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1962 3
1963 2
1964 1
1965 1
1966 1
1967 1
1969 1
1970 1
1972 1
1973 2
1975 3
1976 8
1977 10
1978 4
1979 2
1980 9
1981 8
1982 7
1983 12
1984 10
1985 7
1986 6
1987 22
1988 12
1989 10
1990 10
1991 11
1992 15
1993 16
1994 9
1995 13
1996 12
1997 6
1998 17
1999 14
2000 12
2001 14
2002 15
2003 24
2004 17
2005 24
2006 24
2007 26
2008 30
2009 31
2010 26
2011 19
2012 37
2013 44
2014 28
2015 34
2016 30
2017 21
2018 43
2019 50
2020 67
2021 50
2022 47
2023 44
2024 19

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972 results

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Page 1
Trientine.
[No authors listed] [No authors listed] 2021 Jul 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Jul 19. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000504 Free Books & Documents. Review.
Limited information indicates that trientine is not detectable in breastmilk, and no adverse effects have been reported among breastfed infants whose mothers were taking the drug. ...Based on available data, it appears that trientine is acceptable to use during brea …
Limited information indicates that trientine is not detectable in breastmilk, and no adverse effects have been reported among breastf …
Triethylenetetramine (TETA).
Workplace Environmental Exposure Level (WEEL) Committee; Occupational Alliance for Risk Science (OARS); Toxicology Excellence for Risk Assessment (TERA). Workplace Environmental Exposure Level (WEEL) Committee, et al. Toxicol Ind Health. 2023 Apr;39(4):183-187. doi: 10.1177/07482337231161152. Epub 2023 Mar 20. Toxicol Ind Health. 2023. PMID: 36941775
The WEEL for triethylenetetramine (TETA; CAS No. 112-24-3) was originally established in 1991 and updated in 1998 and 2009. ...
The WEEL for triethylenetetramine (TETA; CAS No. 112-24-3) was originally established in 1991 and updated in 1998 and 2009. ...
Trientine.
[No authors listed] [No authors listed] 2020 Jul 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2020 Jul 25. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643449 Free Books & Documents. Review.
Trientine is an oral copper chelating agent used to treat Wilson disease. Trientine has not been associated with worsening of serum enzyme elevations during therapy or with cases of clinically apparent liver injury with jaundice....
Trientine is an oral copper chelating agent used to treat Wilson disease. Trientine has not been associated with worsening of …
Chelating Agents.
[No authors listed] [No authors listed] 2017 Jan 23. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jan 23. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643849 Free Books & Documents. Review.
It is also effective in lowering levels of other heavy metals including arsenic and mercury. Penicillamine and trientine are orally available and are the mainstays of prevention and therapy of Wilson disease. Trientine is generally better tolerated than penicillamin …
It is also effective in lowering levels of other heavy metals including arsenic and mercury. Penicillamine and trientine are orally a …
Trientine tetrahydrochloride versus penicillamine for maintenance therapy in Wilson disease (CHELATE): a randomised, open-label, non-inferiority, phase 3 trial.
Schilsky ML, Czlonkowska A, Zuin M, Cassiman D, Twardowschy C, Poujois A, Gondim FAA, Denk G, Cury RG, Ott P, Moore J, Ala A, D'Inca R, Couchonnal-Bedoya E, D'Hollander K, Dubois N, Kamlin COF, Weiss KH; CHELATE trial investigators. Schilsky ML, et al. Lancet Gastroenterol Hepatol. 2022 Dec;7(12):1092-1102. doi: 10.1016/S2468-1253(22)00270-9. Epub 2022 Sep 30. Lancet Gastroenterol Hepatol. 2022. PMID: 36183738 Clinical Trial.
Whereas penicillamine is used therapeutically to re-establish copper balance, trientine is indicated for patients with penicillamine intolerance. We aimed to compare penicillamine with trientine tetrahydrochloride (TETA4) for maintenance therapy in patients with Wil …
Whereas penicillamine is used therapeutically to re-establish copper balance, trientine is indicated for patients with penicillamine …
Wilson Disease in Children.
Kerkar N, Rana A. Kerkar N, et al. Clin Liver Dis. 2022 Aug;26(3):473-488. doi: 10.1016/j.cld.2022.03.008. Epub 2022 Jun 25. Clin Liver Dis. 2022. PMID: 35868686 Review.
Treatment remains with zinc and chelating agents such as D-penicillamine and trientine but newer agents and gene therapy are in clinical trials. ...
Treatment remains with zinc and chelating agents such as D-penicillamine and trientine but newer agents and gene therapy are in clini …
[Wilsons disease].
Mareček Z, Brůha R. Mareček Z, et al. Vnitr Lek. 2013 Jul;59(7):578-83. Vnitr Lek. 2013. PMID: 23909262 Review. Czech.
The treatment concerns either removal of copper from the body using chelating agents excreted into the urine (Penicillamine, Trientine) or limitation of copper absorption from the intestine and reducing the toxicity of copper (zinc, ammonium tetrathiomolybdate). ...
The treatment concerns either removal of copper from the body using chelating agents excreted into the urine (Penicillamine, Trientine …
Wilson's disease.
Pandit A, Bavdekar A, Bhave S. Pandit A, et al. Indian J Pediatr. 2002 Sep;69(9):785-91. doi: 10.1007/BF02723693. Indian J Pediatr. 2002. PMID: 12420912 Review.
The mainstay of initial therapy is Cu-chelators like D-Penicillamine, and Trientine for reduction in body copper to sub-toxic levels. Subsequent maintenance therapy is necessarily lifelong with D-Penicillamine, Trientine or Zinc. ...
The mainstay of initial therapy is Cu-chelators like D-Penicillamine, and Trientine for reduction in body copper to sub-toxic levels. …
Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy.
Farrant J, Dodd S, Vaughan C, Reid A, Schmitt M, Garratt C, Akhtar M, Mahmod M, Neubauer S, Cooper RM, Prasad SK, Singh A, Valkovič L, Raman B, Ashkir Z, Clayton D, Baroja O, Duran B, Spowart C, Bedson E, Naish JH, Harrington C, Miller CA; TEMPEST investigators. Farrant J, et al. Heart. 2023 Jul 12;109(15):1175-1182. doi: 10.1136/heartjnl-2022-322271. Heart. 2023. PMID: 37137675 Free PMC article. Clinical Trial.
Trientine was associated with improvements in cardiac structure and function in an open-label study in patients with HCM. METHODS: The Efficacy and Mechanism of Trientine in Patients with Hypertrophic Cardiomyopathy (TEMPEST) trial is a multicentre, double-blind, pa …
Trientine was associated with improvements in cardiac structure and function in an open-label study in patients with HCM. METHODS: Th …
972 results