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A novel class of cycloalkano[b]pyridines as potent and orally active opioid receptor-like 1 antagonists with minimal binding affinity to the hERG K+ channel.
Yoshizumi T, Takahashi H, Miyazoe H, Sugimoto Y, Tsujita T, Kato T, Ito H, Kawamoto H, Hirayama M, Ichikawa D, Azuma-Kanoh T, Ozaki S, Shibata Y, Tani T, Chiba M, Ishii Y, Okuda S, Tadano K, Fukuroda T, Okamoto O, Ohta H. Yoshizumi T, et al. Among authors: tsujita t. J Med Chem. 2008 Jul 10;51(13):4021-9. doi: 10.1021/jm701590h. Epub 2008 Jun 7. J Med Chem. 2008. PMID: 18537234
Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists.
Kobayashi K, Uchiyama M, Ito H, Takahashi H, Yoshizumi T, Sakoh H, Nagatomi Y, Asai M, Miyazoe H, Tsujita T, Hirayama M, Ozaki S, Tani T, Ishii Y, Ohta H, Okamoto O. Kobayashi K, et al. Among authors: tsujita t. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3627-31. doi: 10.1016/j.bmcl.2009.04.116. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19447610
Emerging Role of GCN1 in Disease and Homeostasis.
Tatara Y, Kasai S, Kokubu D, Tsujita T, Mimura J, Itoh K. Tatara Y, et al. Among authors: tsujita t. Int J Mol Sci. 2024 Mar 5;25(5):2998. doi: 10.3390/ijms25052998. Int J Mol Sci. 2024. PMID: 38474243 Free PMC article. Review.
Identification and mechanistic investigation of ellagitannins from Osbeckia octandra that attenuate liver fibrosis via the TGF-β/SMAD signaling pathway.
Bogahawaththa S, Kawamura T, Bandaranayake U, Hirakawa T, Yamada G, Ishino H, Hirohashi T, Kawaguchi SI, Wijesundera KK, Wijayagunawardane MPB, Ishimaru K, Kodithuwakku SP, Tsujita T. Bogahawaththa S, et al. Among authors: tsujita t. Biosci Biotechnol Biochem. 2023 Oct 25;87(11):1295-1309. doi: 10.1093/bbb/zbad114. Biosci Biotechnol Biochem. 2023. PMID: 37580142
Miliary tuberculosis-associated hemophagocytic lymphohistiocytosis with a high level of soluble interleukin-2 receptor successfully treated with concomitant recombinant thrombomodulin: A case report.
Uryu H, Nakamura T, Nakashima D, Yamamoto K, Honda Y, Ishikawa M, Tsujita T, Hata N, Oinuma T, Yamazaki H, Yahagi Y. Uryu H, et al. Among authors: tsujita t. J Infect Chemother. 2023 Mar;29(3):361-366. doi: 10.1016/j.jiac.2022.11.016. Epub 2022 Dec 5. J Infect Chemother. 2023. PMID: 36481565
172 results