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Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes.
Wolf MJ, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, Ringelhan M, Simonavicius N, Egger M, Wohlleber D, Lorentzen A, Einer C, Schulz S, Clavel T, Protzer U, Thiele C, Zischka H, Moch H, Tschöp M, Tumanov AV, Haller D, Unger K, Karin M, Kopf M, Knolle P, Weber A, Heikenwalder M. Wolf MJ, et al. Among authors: tumanov av. Cancer Cell. 2014 Oct 13;26(4):549-64. doi: 10.1016/j.ccell.2014.09.003. Cancer Cell. 2014. PMID: 25314080 Free article.
Expression of lymphotoxin beta governs immunity at two distinct levels.
Junt T, Tumanov AV, Harris N, Heikenwalder M, Zeller N, Kuprash DV, Aguzzi A, Ludewig B, Nedospasov SA, Zinkernagel RM. Junt T, et al. Among authors: tumanov av. Eur J Immunol. 2006 Aug;36(8):2061-75. doi: 10.1002/eji.200626255. Eur J Immunol. 2006. PMID: 16841297 Free article.
Overexpression of lymphotoxin in T cells induces fulminant thymic involution.
Heikenwalder M, Prinz M, Zeller N, Lang KS, Junt T, Rossi S, Tumanov A, Schmidt H, Priller J, Flatz L, Rülicke T, Macpherson AJ, Holländer GA, Nedospasov SA, Aguzzi A. Heikenwalder M, et al. Am J Pathol. 2008 Jun;172(6):1555-70. doi: 10.2353/ajpath.2008.070572. Epub 2008 May 15. Am J Pathol. 2008. PMID: 18483211 Free PMC article.
Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils.
Riffelmacher T, Giles DA, Zahner S, Dicker M, Andreyev AY, McArdle S, Perez-Jeldres T, van der Gracht E, Murray MP, Hartmann N, Tumanov AV, Kronenberg M. Riffelmacher T, et al. Among authors: tumanov av. Mucosal Immunol. 2021 May;14(3):679-690. doi: 10.1038/s41385-021-00378-7. Epub 2021 Feb 10. Mucosal Immunol. 2021. PMID: 33568785 Free PMC article.
T cell-derived lymphotoxin regulates liver regeneration.
Tumanov AV, Koroleva EP, Christiansen PA, Khan MA, Ruddy MJ, Burnette B, Papa S, Franzoso G, Nedospasov SA, Fu YX, Anders RA. Tumanov AV, et al. Gastroenterology. 2009 Feb;136(2):694-704.e4. doi: 10.1053/j.gastro.2008.09.015. Epub 2008 Sep 18. Gastroenterology. 2009. PMID: 18952083 Free PMC article.
86 results