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Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
McAlpine W, Sun L, Wang KW, Liu A, Jain R, San Miguel M, Wang J, Zhang Z, Hayse B, McAlpine SG, Choi JH, Zhong X, Ludwig S, Russell J, Zhan X, Choi M, Li X, Tang M, Moresco EMY, Beutler B, Turer E. McAlpine W, et al. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11523-E11531. doi: 10.1073/pnas.1814753115. Epub 2018 Nov 15. Proc Natl Acad Sci U S A. 2018. PMID: 30442666 Free PMC article.
Creatine maintains intestinal homeostasis and protects against colitis.
Turer E, McAlpine W, Wang KW, Lu T, Li X, Tang M, Zhan X, Wang T, Zhan X, Bu CH, Murray AR, Beutler B. Turer E, et al. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1273-E1281. doi: 10.1073/pnas.1621400114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137860 Free PMC article.
24 results