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Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands.
Norris JD, Joseph JD, Sherk AB, Juzumiene D, Turnbull PS, Rafferty SW, Cui H, Anderson E, Fan D, Dye DA, Deng X, Kazmin D, Chang CY, Willson TM, McDonnell DP. Norris JD, et al. Among authors: turnbull ps. Chem Biol. 2009 Apr 24;16(4):452-60. doi: 10.1016/j.chembiol.2009.01.016. Chem Biol. 2009. PMID: 19389631 Free PMC article.
A new series of estrogen receptor modulators that display selectivity for estrogen receptor beta.
Henke BR, Consler TG, Go N, Hale RL, Hohman DR, Jones SA, Lu AT, Moore LB, Moore JT, Orband-Miller LA, Robinett RG, Shearin J, Spearing PK, Stewart EL, Turnbull PS, Weaver SL, Williams SP, Wisely GB, Lambert MH. Henke BR, et al. Among authors: turnbull ps. J Med Chem. 2002 Dec 5;45(25):5492-505. doi: 10.1021/jm020291h. J Med Chem. 2002. PMID: 12459017
Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats.
Shankaran M, Shearer TW, Stimpson SA, Turner SM, King C, Wong PY, Shen Y, Turnbull PS, Kramer F, Clifton L, Russell A, Hellerstein MK, Evans WJ. Shankaran M, et al. Among authors: turnbull ps. Am J Physiol Endocrinol Metab. 2016 Mar 15;310(6):E405-17. doi: 10.1152/ajpendo.00257.2015. Epub 2015 Dec 29. Am J Physiol Endocrinol Metab. 2016. PMID: 26714847 Free article.
Optimizing Ligand Efficiency of Selective Androgen Receptor Modulators (SARMs).
Handlon AL, Schaller LT, Leesnitzer LM, Merrihew RV, Poole C, Ulrich JC, Wilson JW, Cadilla R, Turnbull P. Handlon AL, et al. ACS Med Chem Lett. 2015 Nov 19;7(1):83-8. doi: 10.1021/acsmedchemlett.5b00377. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819671 Free PMC article.
Effects of a selective androgen receptor modulator (SARM), GSK2849466A, on stress urinary incontinence and bladder activity in rats with ovariectomy-induced oestrogen deficiency.
Kadekawa K, Kawamorita N, Shimizu T, Kurobe M, Turnbull PS, Chandra S, Kambara T, Barton JC, Russell AJ, Yoshimura N. Kadekawa K, et al. Among authors: turnbull ps. BJU Int. 2020 Jun;125(6):911-919. doi: 10.1111/bju.15022. Epub 2020 Mar 20. BJU Int. 2020. PMID: 32011085 Free PMC article.
12 results