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Year Number of Results
1982 1
1984 1
1990 1
1997 1
1999 1
2000 5
2001 2
2003 1
2004 3
2005 1
2006 4
2007 7
2008 10
2009 12
2010 14
2011 10
2012 9
2013 27
2014 19
2015 16
2016 17
2017 22
2018 20
2019 17
2020 22
2021 15
2022 11
2023 12
2024 5

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253 results

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Page 1
The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke.
Kim S, Lee W, Jo H, Sonn SK, Jeong SJ, Seo S, Suh J, Jin J, Kweon HY, Kim TK, Moon SH, Jeon S, Kim JW, Kim YR, Lee EW, Shin HK, Park SH, Oh GT. Kim S, et al. Redox Biol. 2022 Aug;54:102347. doi: 10.1016/j.redox.2022.102347. Epub 2022 May 25. Redox Biol. 2022. PMID: 35688114 Free PMC article.
The representative antioxidant enzyme, Peroxiredoxin-1 (Prdx1), was predominantly expressed in SAM and mediated ROS defense genes, including Txn1, Srx1, Mt1, and Mt2. In the Prdx1(-/-) I/R damaged brain, we observed significantly increased infarction, as assessed by TTC st …
The representative antioxidant enzyme, Peroxiredoxin-1 (Prdx1), was predominantly expressed in SAM and mediated ROS defense genes, including …
Txn1, Ctsd and Cdk4 are key proteins of combination therapy with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats.
Cao W, Li Y, Li M, Zhang X, Liao M. Cao W, et al. Biomed Pharmacother. 2017 Jan;85:611-619. doi: 10.1016/j.biopha.2016.11.071. Epub 2016 Nov 25. Biomed Pharmacother. 2017. PMID: 27894668
A total of 115 differentially expressed proteins containing 84 up-regulated and 31 down-regulated proteins in response to combination therapy were identified. Three differentially expressed proteins (Txn1, Ctsd and Cdk4) involved in antioxidant defense system and the activ …
A total of 115 differentially expressed proteins containing 84 up-regulated and 31 down-regulated proteins in response to combination therap …
The molecular evaluation of thioredoxin (TXN1 & TXN2), thioredoxin reductase 1 (TXNRd1), and oxidative stress markers in a binary rat model of hypo- and hyperthyroidism after treatment with gallic acid.
Najafi Z, Chamani E, Zarban A, Rezaei Z, Sharifzadeh G. Najafi Z, et al. Drug Chem Toxicol. 2023 Nov;46(6):1108-1115. doi: 10.1080/01480545.2022.2131812. Epub 2022 Oct 31. Drug Chem Toxicol. 2023. PMID: 36314079
This study examined the effect of gallic acid (GA) on the oxidative status and expression of liver antioxidant genes including thioredoxin (TXN1 & TXN2) and thioredoxin reductase1 (TXNRd1) in hypo- and hyperthyroid rat models. ...The levels of thyroid hormones and seru …
This study examined the effect of gallic acid (GA) on the oxidative status and expression of liver antioxidant genes including thioredoxin ( …
Thioredoxin1 Binding Metastasis-Associated Lung Adenocarcinoma Transcript 1 Attenuates Inflammation and Apoptosis after Intracerebral Hemorrhage.
Chen R, Xie Q, Xie L, Huang J, Hu L, Lu H, Shi P, He Q, Zhang Q, Gong C, Zhang S, Wang B, Yang G, Yang Q. Chen R, et al. Aging Dis. 2024 May 7;15(3):1384-1397. doi: 10.14336/AD.2023.0507. Aging Dis. 2024. PMID: 37196136 Free PMC article.
Therefore, we identified RBPs distinctively expressed after ICH by screening and determined thioredoxin1 (Txn1) as one of the most distinctive RBPs. We employed an ICH model and in vitro experiments to investigate the role of Txn1 in ICH. ...Additionally, adeno-asso …
Therefore, we identified RBPs distinctively expressed after ICH by screening and determined thioredoxin1 (Txn1) as one of the most di …
Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
Sharma RS, Harrison DJ, Kisielewski D, Cassidy DM, McNeilly AD, Gallagher JR, Walsh SV, Honda T, McCrimmon RJ, Dinkova-Kostova AT, Ashford MLJ, Dillon JF, Hayes JD. Sharma RS, et al. Cell Mol Gastroenterol Hepatol. 2017 Dec 13;5(3):367-398. doi: 10.1016/j.jcmgh.2017.11.016. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29552625 Free PMC article.
Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressor.
Jabbar S, Mathews P, Wang X, Sundaramoorthy P, Chu E, Piryani SO, Ding S, Shen X, Doan PL, Kang Y. Jabbar S, et al. Exp Hematol Oncol. 2022 Oct 31;11(1):83. doi: 10.1186/s40164-022-00329-3. Exp Hematol Oncol. 2022. PMID: 36316713 Free PMC article.
METHODS: TXN1 conditional knockout mice (ROSA-CreER-TXN1(fl/fl)) and TXN1(fl/fl) control mice were used. ...Furthermore, we found that knocking out of TXN1 renders HSPCs more sensitive to radiation and treatment with recombinant TXN1 promotes th …
METHODS: TXN1 conditional knockout mice (ROSA-CreER-TXN1(fl/fl)) and TXN1(fl/fl) control mice were used. ...Furthermore …
In focus in HCB.
Taatjes DJ, Roth J. Taatjes DJ, et al. Histochem Cell Biol. 2021 Jan;155(1):1-8. doi: 10.1007/s00418-020-01958-7. Epub 2021 Jan 20. Histochem Cell Biol. 2021. PMID: 33469707 No abstract available.
Thioredoxin deficiency increases oxidative stress and causes bilateral symmetrical degeneration in rat midbrain.
Ohmori I, Ouchida M, Imai H, Ishida S, Toyokuni S, Mashimo T. Ohmori I, et al. Neurobiol Dis. 2022 Dec;175:105921. doi: 10.1016/j.nbd.2022.105921. Epub 2022 Nov 11. Neurobiol Dis. 2022. PMID: 36372289 Free article.
A phenotype-driven study of N-ethyl-N-nitrosourea-mutated rats with wild-running seizures revealed the importance of Txn1 mutations in CNS degeneration. Genetic mapping identified Txn1-F54L in the epileptic rats. ...Neurons in Txn1-F54L rats showed morphologi …
A phenotype-driven study of N-ethyl-N-nitrosourea-mutated rats with wild-running seizures revealed the importance of Txn1 mutations i …
Cell survival following radiation exposure requires miR-525-3p mediated suppression of ARRB1 and TXN1.
Kraemer A, Barjaktarovic Z, Sarioglu H, Winkler K, Eckardt-Schupp F, Tapio S, Atkinson MJ, Moertl S. Kraemer A, et al. PLoS One. 2013 Oct 16;8(10):e77484. doi: 10.1371/journal.pone.0077484. eCollection 2013. PLoS One. 2013. PMID: 24147004 Free PMC article.
Individual analysis of these direct targets by RNAi-mediated knockdown established that ARRB1, TXN1 and HSPA9 are essential miR-525-3p-dependent regulators of radiation sensitivity. CONCLUSION: The transient up-regulation of miR-525-3p, and the resultant repression of its …
Individual analysis of these direct targets by RNAi-mediated knockdown established that ARRB1, TXN1 and HSPA9 are essential miR-525-3 …
253 results