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27 results

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Page 1
Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1.
Ortiz C, Klein S, Reul WH, Magdaleno F, Gröschl S, Dietrich P, Schierwagen R, Uschner FE, Torres S, Hieber C, Meier C, Kraus N, Tyc O, Brol M, Zeuzem S, Welsch C, Poglitsch M, Hellerbrand C, Alfonso-Prieto M, Mira F, Keller UAD, Tetzner A, Moore A, Walther T, Trebicka J. Ortiz C, et al. Among authors: tyc o. Cell Rep. 2023 Feb 28;42(2):112059. doi: 10.1016/j.celrep.2023.112059. Epub 2023 Jan 31. Cell Rep. 2023. PMID: 36729833 Free PMC article.
Colon Cancer Microbiome Landscaping: Differences in Right- and Left-Sided Colon Cancer and a Tumor Microbiome-Ileal Microbiome Association.
Kneis B, Wirtz S, Weber K, Denz A, Gittler M, Geppert C, Brunner M, Krautz C, Siebenhüner AR, Schierwagen R, Tyc O, Agaimy A, Grützmann R, Trebicka J, Kersting S, Langheinrich M. Kneis B, et al. Among authors: tyc o. Int J Mol Sci. 2023 Feb 7;24(4):3265. doi: 10.3390/ijms24043265. Int J Mol Sci. 2023. PMID: 36834671 Free PMC article.
The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.
Bachtler N, Torres S, Ortiz C, Schierwagen R, Tyc O, Hieber C, Berres ML, Meier C, Kraus N, Zeuzem S, Nijmeijer B, Pronk S, Trebicka J, Klein S. Bachtler N, et al. Among authors: tyc o. PLoS One. 2023 Jan 31;18(1):e0270288. doi: 10.1371/journal.pone.0270288. eCollection 2023. PLoS One. 2023. PMID: 36719899 Free PMC article.
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis.
Torres S, Ortiz C, Bachtler N, Gu W, Grünewald LD, Kraus N, Schierwagen R, Hieber C, Meier C, Tyc O, Joseph Brol M, Uschner FE, Nijmeijer B, Welsch C, Berres ML, Garcia-Ruiz C, Fernandez-Checa JC, Trautwein C, Vogl TJ, Zeuzem S, Trebicka J, Klein S. Torres S, et al. Among authors: tyc o. Hepatology. 2023 Apr 1;77(4):1228-1240. doi: 10.1002/hep.32746. Epub 2022 Oct 13. Hepatology. 2023. PMID: 35993369 Free PMC article.
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.
Torres S, Brol MJ, Magdaleno F, Schierwagen R, Uschner FE, Klein S, Ortiz C, Tyc O, Bachtler N, Stunden J, Bertheloot D, Kitanovic A, Sanchez B, Schrum J, Roush WR, Franchi L, Byth K, Latz E, Trebicka J. Torres S, et al. Among authors: tyc o. Front Mol Biosci. 2021 Aug 13;8:715765. doi: 10.3389/fmolb.2021.715765. eCollection 2021. Front Mol Biosci. 2021. PMID: 34513923 Free PMC article.
β-Arrestin2 is increased in liver fibrosis in humans and rodents.
Schierwagen R, Dietrich P, Klein S, Uschner FE, Ortiz C, Tyc O, Torres S, Hellerbrand C, Sauerbruch T, Trebicka J. Schierwagen R, et al. Among authors: tyc o. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27082-27084. doi: 10.1073/pnas.2014337117. Proc Natl Acad Sci U S A. 2020. PMID: 33144522 Free PMC article. No abstract available.
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease.
Tyc O, Jansen C, Schierwagen R, Uschner FE, Israelsen M, Klein S, Ortiz C, Strassburg CP, Zeuzem S, Gu W, Torres S, Praktiknjo M, Kersting S, Langheinrich M, Nattermann J, Servant F, Arumugam M, Krag A, Lelouvier B, Weismüller TJ, Trebicka J. Tyc O, et al. Liver Transpl. 2020 Dec;26(12):1652-1657. doi: 10.1002/lt.25882. Epub 2020 Oct 7. Liver Transpl. 2020. PMID: 32885580 Free PMC article. No abstract available.
Microbiome Patterns in Matched Bile, Duodenal, Pancreatic Tumor Tissue, Drainage, and Stool Samples: Association with Preoperative Stenting and Postoperative Pancreatic Fistula Development.
Langheinrich M, Wirtz S, Kneis B, Gittler MM, Tyc O, Schierwagen R, Brunner M, Krautz C, Weber GF, Pilarsky C, Trebicka J, Agaimy A, Grützmann R, Kersting S. Langheinrich M, et al. Among authors: tyc o. J Clin Med. 2020 Aug 28;9(9):2785. doi: 10.3390/jcm9092785. J Clin Med. 2020. PMID: 32872220 Free PMC article.
27 results