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Post-transcriptional splicing can occur in a slow-moving zone around the gene.
Coté A, O'Farrell A, Dardani I, Dunagin M, Coté C, Wan Y, Bayatpour S, Drexler HL, Alexander KA, Chen F, Wassie AT, Patel R, Pham K, Boyden ES, Berger S, Phillips-Cremins J, Churchman LS, Raj A. Coté A, et al. Elife. 2024 Apr 5;12:RP91357. doi: 10.7554/eLife.91357. Elife. 2024. PMID: 38577979 Free PMC article.
ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ.
Dardani I, Emert BL, Goyal Y, Jiang CL, Kaur A, Lee J, Rouhanifard SH, Alicea GM, Fane ME, Xiao M, Herlyn M, Weeraratna AT, Raj A. Dardani I, et al. Nat Methods. 2022 Nov;19(11):1403-1410. doi: 10.1038/s41592-022-01653-6. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280724 Free PMC article.
Cohesin-mediated loop anchors confine the locations of human replication origins.
Emerson DJ, Zhao PA, Cook AL, Barnett RJ, Klein KN, Saulebekova D, Ge C, Zhou L, Simandi Z, Minsk MK, Titus KR, Wang W, Gong W, Zhang D, Yang L, Venev SV, Gibcus JH, Yang H, Sasaki T, Kanemaki MT, Yue F, Dekker J, Chen CL, Gilbert DM, Phillips-Cremins JE. Emerson DJ, et al. Nature. 2022 Jun;606(7915):812-819. doi: 10.1038/s41586-022-04803-0. Epub 2022 Jun 8. Nature. 2022. PMID: 35676475 Free PMC article.
p53 mediates target gene association with nuclear speckles for amplified RNA expression.
Alexander KA, Coté A, Nguyen SC, Zhang L, Gholamalamdari O, Agudelo-Garcia P, Lin-Shiao E, Tanim KMA, Lim J, Biddle N, Dunagin MC, Good CR, Mendoza MR, Little SC, Belmont A, Joyce EF, Raj A, Berger SL. Alexander KA, et al. Mol Cell. 2021 Apr 15;81(8):1666-1681.e6. doi: 10.1016/j.molcel.2021.03.006. Epub 2021 Apr 5. Mol Cell. 2021. PMID: 33823140 Free PMC article.
46 results